ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Methylated-DNA--protein-cysteine methyltransferase

Intramolecular
Cysteine 5 and cysteine 24
A redox-regulated disulphide may form within Methylated-DNA--protein-cysteine methyltransferase between cysteines 5 and 24.

Details

Redox score ?
82
PDB code
1t39
Structure name
human o6-alkylguanine-dna alkyltransferase covalently crosslinked to dna
Structure deposition date
2004-04-25
Thiol separation (Å)
3
Half-sphere exposure sum ?
nan
Minimum pKa ?
8
% buried
nan
Peptide accession
P16455
Residue number A
5
Residue number B
24
Peptide name
Methylated-DNA--protein-cysteine methyltransferase

Ligandability

Cysteine 5 of Methylated-DNA--protein-cysteine methyltransferase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 24 of Methylated-DNA--protein-cysteine methyltransferase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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