ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Atrial natriuretic peptide receptor 3

Intramolecular
Cysteine 108 and cysteine 136
Cysteine 213 and cysteine 261
A redox-regulated disulphide may form within Atrial natriuretic peptide receptor 3 between cysteines 108 and 136 (63 and 91 respectively in this structure).

Details

Redox score ?
81
PDB code
1jdp
Structure name
crystal structure of hormone/receptor complex
Structure deposition date
2001-06-14
Thiol separation (Å)
2
Half-sphere exposure sum ?
79
Minimum pKa ?
nan
% buried
nan
Peptide accession
P17342
Residue number A
108
Residue number B
136
Peptide name
Atrial natriuretic peptide receptor 3

Ligandability

Cysteine 108 of Atrial natriuretic peptide receptor 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 136 of Atrial natriuretic peptide receptor 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Atrial natriuretic peptide receptor 3 between cysteines 213 and 261 (168 and 216 respectively in this structure).

Details

Redox score ?
79
PDB code
1jdp
Structure name
crystal structure of hormone/receptor complex
Structure deposition date
2001-06-14
Thiol separation (Å)
2
Half-sphere exposure sum ?
80
Minimum pKa ?
nan
% buried
nan
Peptide accession
P17342
Residue number A
213
Residue number B
261
Peptide name
Atrial natriuretic peptide receptor 3

Ligandability

Cysteine 213 of Atrial natriuretic peptide receptor 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 261 of Atrial natriuretic peptide receptor 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: