a tool for identifying drug-targetable redox-active disulphides

Transcription factor JunD

Intermolecular

Cysteine 172 of Protein FosB and cysteine 285

A redox-regulated disulphide may form between cysteine 172 of Protein FosB and cysteine 285 of Transcription factor JunD.

Details

Redox score ?

73

PDB code

Structure name

transcription factor fosb/jund bzip domain

Structure deposition date

2017-05-04

Thiol separation (Å)

5

Half-sphere exposure sum ?

45

Minimum pK_a ?

nan

% buried

0

Peptide A name

Protein FosB

Peptide B name

Transcription factor JunD

Peptide A accession

Peptide B accession

Peptide A residue number

172

Peptide B residue number

285

Ligandability

Cysteine 172 of Protein FosB

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 285 of Transcription factor JunD

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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