Vinculin

Intramolecular

A redox-regulated disulphide may form within Vinculin between cysteines 325 and 545. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

7ktt

Structure name

cryogenic electron microscopy model of full-length human metavinculin

Structure deposition date

2020-11-24

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

P18206

Residue number A

325

Residue number B

545

Peptide name

Vinculin

Ligandability

Cysteine 325 of Vinculin

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.