ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

Intramolecular
Cysteine 68 and cysteine 76
A redox-regulated disulphide may form within Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma between cysteines 68 and 76.

Details

Redox score ?
nan
PDB code
2ju4
Structure name
nmr structure of the gamma subunit of cgmp phosphodiesterase
Structure deposition date
2007-08-14
Thiol separation (Å)
10
Half-sphere exposure sum ?
33
Minimum pKa ?
11
% buried
16
Peptide accession
P04972
Residue number A
68
Residue number B
76
Peptide name
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

Ligandability

Cysteine 68 of Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

Cysteine 76 of Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

Cysteine 76 in protein B could not be asigned to a Uniprot residue.
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