ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Regulator of chromosome condensation

Intramolecular
Cysteine 308 and cysteine 352
A redox-regulated disulphide may form within Regulator of chromosome condensation between cysteines 308 and 352. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
29
PDB code
5tbk
Structure name
crystal structure of human importin a3 bound to rcc1
Structure deposition date
2016-09-12
Thiol separation (Å)
9
Half-sphere exposure sum ?
98
Minimum pKa ?
12
% buried
100
Peptide accession
P18754
Residue number A
308
Residue number B
352
Peptide name
Regulator of chromosome condensation

Ligandability

Cysteine 308 of Regulator of chromosome condensation

Cysteine 352 of Regulator of chromosome condensation

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