ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Complement receptor type 2

Intramolecular
Cysteine 118 and cysteine 146
Cysteine 23 and cysteine 65
Cysteine 51 and cysteine 82
Cysteine 91 and cysteine 132
A redox-regulated disulphide may form within Complement receptor type 2 between cysteines 118 and 146 (99 and 127 respectively in this structure).

Details

Redox score ?
86
PDB code
1ghq
Structure name
cr2-c3d complex structure
Structure deposition date
2001-01-11
Thiol separation (Å)
2
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
P20023
Residue number A
118
Residue number B
146
Peptide name
Complement receptor type 2

Ligandability

Cysteine 118 of Complement receptor type 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 146 of Complement receptor type 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Complement receptor type 2 between cysteines 23 and 65 (4 and 46 respectively in this structure).

Details

Redox score ?
86
PDB code
1ghq
Structure name
cr2-c3d complex structure
Structure deposition date
2001-01-11
Thiol separation (Å)
2
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P20023
Residue number A
23
Residue number B
65
Peptide name
Complement receptor type 2

Ligandability

Cysteine 23 of Complement receptor type 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 65 of Complement receptor type 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Complement receptor type 2 between cysteines 51 and 82 (32 and 63 respectively in this structure).

Details

Redox score ?
85
PDB code
1ghq
Structure name
cr2-c3d complex structure
Structure deposition date
2001-01-11
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P20023
Residue number A
51
Residue number B
82
Peptide name
Complement receptor type 2

Ligandability

Cysteine 51 of Complement receptor type 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 82 of Complement receptor type 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Complement receptor type 2 between cysteines 91 and 132 (72 and 113 respectively in this structure).

Details

Redox score ?
83
PDB code
1ghq
Structure name
cr2-c3d complex structure
Structure deposition date
2001-01-11
Thiol separation (Å)
2
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
P20023
Residue number A
91
Residue number B
132
Peptide name
Complement receptor type 2

Ligandability

Cysteine 91 of Complement receptor type 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 132 of Complement receptor type 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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