ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

HLA class II histocompatibility antigen, DP alpha 1 chain

Intramolecular
Cysteine 138 and cysteine 194
A redox-regulated disulphide may form within HLA class II histocompatibility antigen, DP alpha 1 chain between cysteines 138 and 194 (107 and 163 respectively in this structure).

Details

Redox score ?
79
PDB code
7t2b
Structure name
crystal structure of the 5f tcr in complex with hla-dp4-ply
Structure deposition date
2021-12-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
80
Minimum pKa ?
nan
% buried
nan
Peptide accession
P20036
Residue number A
138
Residue number B
194
Peptide name
HLA class II histocompatibility antigen, DP alpha 1 chain

Ligandability

Cysteine 138 of HLA class II histocompatibility antigen, DP alpha 1 chain

Cysteine 194 of HLA class II histocompatibility antigen, DP alpha 1 chain

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