ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Cyclin-A2

Intermolecular
Cysteine 327 and cysteine 327
A redox-regulated disulphide may form between two units of Cyclin-A2 at cysteines 327 and 327.

Details

Redox score ?
85
PDB code
2c6t
Structure name
crystal structure of the human cdk2 complexed with the triazolopyrimidine inhibitor
Structure deposition date
2005-11-11
Thiol separation (Å)
3
Half-sphere exposure sum ?
74
Minimum pKa ?
5
% buried
72
Peptide A name
Cyclin-A2
Peptide B name
Cyclin-A2
Peptide A accession
P20248
Peptide B accession
P20248
Peptide A residue number
327
Peptide B residue number
327

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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