Nuclear receptor subfamily 1 group D member 1
Intramolecular
Cysteine 169 and cysteine 175
Cysteine 169 and cysteine 185
Cysteine 169 and cysteine 188
Cysteine 175 and cysteine 185
Cysteine 185 and cysteine 188
Cysteine 175 and cysteine 188
Cysteine 149 and cysteine 152
Cysteine 135 and cysteine 152
Cysteine 132 and cysteine 152
Cysteine 132 and cysteine 135
More...Cysteine 132 and cysteine 149
Cysteine 135 and cysteine 149
Cysteine 152 and cysteine 193
Cysteine 132 and cysteine 193
Cysteine 149 and cysteine 193
Cysteine 135 and cysteine 193
1hlz A 37 A 43
A redox-regulated disulphide may form within Nuclear receptor subfamily 1 group D member 1 between cysteines 169 and 175 (37 and 43 respectively in this structure).
Details
Redox score ?
95
PDB code
1hlz
Structure name
crystal structure of the orphan nuclear receptor rev- erb(alpha) dna-binding domain bound to its cognate response element
Structure deposition date
2000-12-04
Thiol separation (Å)
3
Half-sphere exposure sum ?
42
Minimum pKa ?
6
% buried
0
Peptide accession
P20393
Residue number A
169
Residue number B
175
Peptide name
Nuclear receptor subfamily 1 group D member 1
Ligandability
Cysteine 169 of Nuclear receptor subfamily 1 group D member 1
Cysteine 175 of Nuclear receptor subfamily 1 group D member 1
1hlz A 37 A 53
A redox-regulated disulphide may form within Nuclear receptor subfamily 1 group D member 1 between cysteines 169 and 185 (37 and 53 respectively in this structure).
Details
Redox score ?
92
PDB code
1hlz
Structure name
crystal structure of the orphan nuclear receptor rev- erb(alpha) dna-binding domain bound to its cognate response element
Structure deposition date
2000-12-04
Thiol separation (Å)
3
Half-sphere exposure sum ?
44
Minimum pKa ?
6
% buried
0
Peptide accession
P20393
Residue number A
169
Residue number B
185
Peptide name
Nuclear receptor subfamily 1 group D member 1
Ligandability
Cysteine 169 of Nuclear receptor subfamily 1 group D member 1
Cysteine 185 of Nuclear receptor subfamily 1 group D member 1
1a6y B 137 B 156
A redox-regulated disulphide may form within Nuclear receptor subfamily 1 group D member 1 between cysteines 169 and 188 (137 and 156 respectively in this structure).
Details
Redox score ?
87
PDB code
1a6y
Structure name
reverba orphan nuclear receptor/dna complex
Structure deposition date
1998-03-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
6
% buried
2
Peptide accession
P20393
Residue number A
169
Residue number B
188
Peptide name
Nuclear receptor subfamily 1 group D member 1
Ligandability
Cysteine 169 of Nuclear receptor subfamily 1 group D member 1
Cysteine 188 of Nuclear receptor subfamily 1 group D member 1
1hlz A 43 A 53
A redox-regulated disulphide may form within Nuclear receptor subfamily 1 group D member 1 between cysteines 175 and 185 (43 and 53 respectively in this structure).
Details
Redox score ?
86
PDB code
1hlz
Structure name
crystal structure of the orphan nuclear receptor rev- erb(alpha) dna-binding domain bound to its cognate response element
Structure deposition date
2000-12-04
Thiol separation (Å)
3
Half-sphere exposure sum ?
50
Minimum pKa ?
10
% buried
0
Peptide accession
P20393
Residue number A
175
Residue number B
185
Peptide name
Nuclear receptor subfamily 1 group D member 1
Ligandability
Cysteine 175 of Nuclear receptor subfamily 1 group D member 1
Cysteine 185 of Nuclear receptor subfamily 1 group D member 1
1ga5 E 53 E 56
A redox-regulated disulphide may form within Nuclear receptor subfamily 1 group D member 1 between cysteines 185 and 188 (53 and 56 respectively in this structure).
Details
Redox score ?
85
PDB code
1ga5
Structure name
crystal structure of the orphan nuclear receptor rev-erb(alpha) dna- binding domain bound to its cognate response element
Structure deposition date
2000-11-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
6
% buried
0
Peptide accession
P20393
Residue number A
185
Residue number B
188
Peptide name
Nuclear receptor subfamily 1 group D member 1
Ligandability
Cysteine 185 of Nuclear receptor subfamily 1 group D member 1
Cysteine 188 of Nuclear receptor subfamily 1 group D member 1
1a6y A 143 A 156
A redox-regulated disulphide may form within Nuclear receptor subfamily 1 group D member 1 between cysteines 175 and 188 (143 and 156 respectively in this structure).
Details
Redox score ?
83
PDB code
1a6y
Structure name
reverba orphan nuclear receptor/dna complex
Structure deposition date
1998-03-04
Thiol separation (Å)
3
Half-sphere exposure sum ?
54
Minimum pKa ?
8
% buried
5
Peptide accession
P20393
Residue number A
175
Residue number B
188
Peptide name
Nuclear receptor subfamily 1 group D member 1
Ligandability
Cysteine 175 of Nuclear receptor subfamily 1 group D member 1
Cysteine 188 of Nuclear receptor subfamily 1 group D member 1
1a6y B 118 B 121
A redox-regulated disulphide may form within Nuclear receptor subfamily 1 group D member 1 between cysteines 149 and 152 (118 and 121 respectively in this structure).
Details
Redox score ?
83
PDB code
1a6y
Structure name
reverba orphan nuclear receptor/dna complex
Structure deposition date
1998-03-04
Thiol separation (Å)
3
Half-sphere exposure sum ?
73
Minimum pKa ?
4
% buried
86
Peptide accession
P20393
Residue number A
149
Residue number B
152
Peptide name
Nuclear receptor subfamily 1 group D member 1
Ligandability
Cysteine 149 of Nuclear receptor subfamily 1 group D member 1
Cysteine 152 of Nuclear receptor subfamily 1 group D member 1
1ga5 B 4 B 21
A redox-regulated disulphide may form within Nuclear receptor subfamily 1 group D member 1 between cysteines 135 and 152 (4 and 21 respectively in this structure).
Details
Redox score ?
79
PDB code
1ga5
Structure name
crystal structure of the orphan nuclear receptor rev-erb(alpha) dna- binding domain bound to its cognate response element
Structure deposition date
2000-11-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
77
Minimum pKa ?
5
% buried
78
Peptide accession
P20393
Residue number A
135
Residue number B
152
Peptide name
Nuclear receptor subfamily 1 group D member 1
Ligandability
Cysteine 135 of Nuclear receptor subfamily 1 group D member 1
Cysteine 152 of Nuclear receptor subfamily 1 group D member 1
1hlz B 1 B 21
A redox-regulated disulphide may form within Nuclear receptor subfamily 1 group D member 1 between cysteines 132 and 152 (1 and 21 respectively in this structure).
Details
Redox score ?
69
PDB code
1hlz
Structure name
crystal structure of the orphan nuclear receptor rev- erb(alpha) dna-binding domain bound to its cognate response element
Structure deposition date
2000-12-04
Thiol separation (Å)
3
Half-sphere exposure sum ?
73
Minimum pKa ?
13
% buried
nan
Peptide accession
P20393
Residue number A
132
Residue number B
152
Peptide name
Nuclear receptor subfamily 1 group D member 1
Ligandability
Cysteine 132 of Nuclear receptor subfamily 1 group D member 1
Cysteine 152 of Nuclear receptor subfamily 1 group D member 1
1a6y B 101 B 104
A redox-regulated disulphide may form within Nuclear receptor subfamily 1 group D member 1 between cysteines 132 and 135 (101 and 104 respectively in this structure).
Details
Redox score ?
68
PDB code
1a6y
Structure name
reverba orphan nuclear receptor/dna complex
Structure deposition date
1998-03-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
68
Minimum pKa ?
13
% buried
nan
Peptide accession
P20393
Residue number A
132
Residue number B
135
Peptide name
Nuclear receptor subfamily 1 group D member 1
Ligandability
Cysteine 132 of Nuclear receptor subfamily 1 group D member 1
Cysteine 135 of Nuclear receptor subfamily 1 group D member 1
1hlz B 1 B 18
A redox-regulated disulphide may form within Nuclear receptor subfamily 1 group D member 1 between cysteines 132 and 149 (1 and 18 respectively in this structure).
Details
Redox score ?
66
PDB code
1hlz
Structure name
crystal structure of the orphan nuclear receptor rev- erb(alpha) dna-binding domain bound to its cognate response element
Structure deposition date
2000-12-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
63
Minimum pKa ?
13
% buried
80
Peptide accession
P20393
Residue number A
132
Residue number B
149
Peptide name
Nuclear receptor subfamily 1 group D member 1
Ligandability
Cysteine 132 of Nuclear receptor subfamily 1 group D member 1
Cysteine 149 of Nuclear receptor subfamily 1 group D member 1
1hlz A 4 A 18
A redox-regulated disulphide may form within Nuclear receptor subfamily 1 group D member 1 between cysteines 135 and 149 (4 and 18 respectively in this structure).
Details
Redox score ?
64
PDB code
1hlz
Structure name
crystal structure of the orphan nuclear receptor rev- erb(alpha) dna-binding domain bound to its cognate response element
Structure deposition date
2000-12-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
62
Minimum pKa ?
13
% buried
nan
Peptide accession
P20393
Residue number A
135
Residue number B
149
Peptide name
Nuclear receptor subfamily 1 group D member 1
Ligandability
Cysteine 135 of Nuclear receptor subfamily 1 group D member 1
Cysteine 149 of Nuclear receptor subfamily 1 group D member 1
1a6y B 121 B 161
A redox-regulated disulphide may form within Nuclear receptor subfamily 1 group D member 1 between cysteines 152 and 193 (121 and 161 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
57
PDB code
1a6y
Structure name
reverba orphan nuclear receptor/dna complex
Structure deposition date
1998-03-04
Thiol separation (Å)
5
Half-sphere exposure sum ?
81
Minimum pKa ?
12
% buried
91
Peptide accession
P20393
Residue number A
152
Residue number B
193
Peptide name
Nuclear receptor subfamily 1 group D member 1
Ligandability
Cysteine 152 of Nuclear receptor subfamily 1 group D member 1
Cysteine 193 of Nuclear receptor subfamily 1 group D member 1
1ga5 F 1 F 61
A redox-regulated disulphide may form within Nuclear receptor subfamily 1 group D member 1 between cysteines 132 and 193 (1 and 61 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
1ga5
Structure name
crystal structure of the orphan nuclear receptor rev-erb(alpha) dna- binding domain bound to its cognate response element
Structure deposition date
2000-11-29
Thiol separation (Å)
7
Half-sphere exposure sum ?
72
Minimum pKa ?
11
% buried
79
Peptide accession
P20393
Residue number A
132
Residue number B
193
Peptide name
Nuclear receptor subfamily 1 group D member 1
Ligandability
Cysteine 132 of Nuclear receptor subfamily 1 group D member 1
Cysteine 193 of Nuclear receptor subfamily 1 group D member 1
1ga5 B 18 B 61
A redox-regulated disulphide may form within Nuclear receptor subfamily 1 group D member 1 between cysteines 149 and 193 (18 and 61 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
1ga5
Structure name
crystal structure of the orphan nuclear receptor rev-erb(alpha) dna- binding domain bound to its cognate response element
Structure deposition date
2000-11-29
Thiol separation (Å)
8
Half-sphere exposure sum ?
66
Minimum pKa ?
11
% buried
92
Peptide accession
P20393
Residue number A
149
Residue number B
193
Peptide name
Nuclear receptor subfamily 1 group D member 1
Ligandability
Cysteine 149 of Nuclear receptor subfamily 1 group D member 1
Cysteine 193 of Nuclear receptor subfamily 1 group D member 1
1a6y A 104 A 161
A redox-regulated disulphide may form within Nuclear receptor subfamily 1 group D member 1 between cysteines 135 and 193 (104 and 161 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
1a6y
Structure name
reverba orphan nuclear receptor/dna complex
Structure deposition date
1998-03-04
Thiol separation (Å)
9
Half-sphere exposure sum ?
72
Minimum pKa ?
12
% buried
81
Peptide accession
P20393
Residue number A
135
Residue number B
193
Peptide name
Nuclear receptor subfamily 1 group D member 1
Ligandability
Cysteine 135 of Nuclear receptor subfamily 1 group D member 1
Cysteine 193 of Nuclear receptor subfamily 1 group D member 1
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