Tumor necrosis factor alpha-induced protein 3
Intramolecular
Cysteine 607 and cysteine 612
Cysteine 612 and cysteine 627
Cysteine 392 and cysteine 404
Cysteine 387 and cysteine 392
Cysteine 607 and cysteine 624
Cysteine 387 and cysteine 404
Cysteine 762 and cysteine 767
Cysteine 387 and cysteine 407
Cysteine 404 and cysteine 407
Cysteine 767 and cysteine 782
More...Cysteine 392 and cysteine 407
Cysteine 767 and cysteine 779
Cysteine 762 and cysteine 779
Cysteine 762 and cysteine 782
Cysteine 607 and cysteine 627
Cysteine 612 and cysteine 624
Cysteine 775 and cysteine 779
Cysteine 779 and cysteine 782
Cysteine 624 and cysteine 627
Cysteine 762 and cysteine 775
Cysteine 775 and cysteine 782
Cysteine 200 and cysteine 243
3oj3 O 607 O 612
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 607 and 612.
Details
Redox score ?
88
PDB code
3oj3
Structure name
crystal structure of the a20 znf4 and ubiquitin complex
Structure deposition date
2010-08-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
48
Minimum pKa ?
6
% buried
12
Peptide accession
P21580
Residue number A
607
Residue number B
612
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 607 of Tumor necrosis factor alpha-induced protein 3
Cysteine 612 of Tumor necrosis factor alpha-induced protein 3
3oj3 O 612 O 627
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 612 and 627.
Details
Redox score ?
88
PDB code
3oj3
Structure name
crystal structure of the a20 znf4 and ubiquitin complex
Structure deposition date
2010-08-20
Thiol separation (Å)
3
Half-sphere exposure sum ?
49
Minimum pKa ?
6
% buried
9
Peptide accession
P21580
Residue number A
612
Residue number B
627
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 612 of Tumor necrosis factor alpha-induced protein 3
Cysteine 627 of Tumor necrosis factor alpha-induced protein 3
2eqg A 19 A 31
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 392 and 404 (19 and 31 respectively in this structure).
Details
Redox score ?
87
PDB code
2eqg
Structure name
solution structure of the first a20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3
Structure deposition date
2007-03-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
50
Minimum pKa ?
7
% buried
0
Peptide accession
P21580
Residue number A
392
Residue number B
404
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 392 of Tumor necrosis factor alpha-induced protein 3
Cysteine 404 of Tumor necrosis factor alpha-induced protein 3
2eqg A 14 A 19
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 387 and 392 (14 and 19 respectively in this structure).
Details
Redox score ?
86
PDB code
2eqg
Structure name
solution structure of the first a20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3
Structure deposition date
2007-03-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
43
Minimum pKa ?
8
% buried
0
Peptide accession
P21580
Residue number A
387
Residue number B
392
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 387 of Tumor necrosis factor alpha-induced protein 3
Cysteine 392 of Tumor necrosis factor alpha-induced protein 3
3oj4 F 607 F 624
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 607 and 624.
Details
Redox score ?
85
PDB code
3oj4
Structure name
crystal structure of the a20 znf4, ubiquitin and ubch5a complex
Structure deposition date
2010-08-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
64
Minimum pKa ?
6
% buried
27
Peptide accession
P21580
Residue number A
607
Residue number B
624
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 607 of Tumor necrosis factor alpha-induced protein 3
Cysteine 624 of Tumor necrosis factor alpha-induced protein 3
2eqg A 14 A 31
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 387 and 404 (14 and 31 respectively in this structure).
Details
Redox score ?
84
PDB code
2eqg
Structure name
solution structure of the first a20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3
Structure deposition date
2007-03-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
7
% buried
0
Peptide accession
P21580
Residue number A
387
Residue number B
404
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 387 of Tumor necrosis factor alpha-induced protein 3
Cysteine 404 of Tumor necrosis factor alpha-induced protein 3
3vux G 762 G 767
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 762 and 767.
Details
Redox score ?
84
PDB code
3vux
Structure name
crystal structure of a20 zf7 in complex with linear ubiquitin, form ii
Structure deposition date
2012-07-09
Thiol separation (Å)
4
Half-sphere exposure sum ?
60
Minimum pKa ?
6
% buried
32
Peptide accession
P21580
Residue number A
762
Residue number B
767
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 762 of Tumor necrosis factor alpha-induced protein 3
Cysteine 767 of Tumor necrosis factor alpha-induced protein 3
2eqg A 14 A 34
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 387 and 407 (14 and 34 respectively in this structure).
Details
Redox score ?
83
PDB code
2eqg
Structure name
solution structure of the first a20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3
Structure deposition date
2007-03-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
50
Minimum pKa ?
8
% buried
0
Peptide accession
P21580
Residue number A
387
Residue number B
407
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 387 of Tumor necrosis factor alpha-induced protein 3
Cysteine 407 of Tumor necrosis factor alpha-induced protein 3
2eqg A 31 A 34
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 404 and 407 (31 and 34 respectively in this structure).
Details
Redox score ?
82
PDB code
2eqg
Structure name
solution structure of the first a20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3
Structure deposition date
2007-03-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
7
% buried
0
Peptide accession
P21580
Residue number A
404
Residue number B
407
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 404 of Tumor necrosis factor alpha-induced protein 3
Cysteine 407 of Tumor necrosis factor alpha-induced protein 3
3vux E 767 E 782
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 767 and 782.
Details
Redox score ?
81
PDB code
3vux
Structure name
crystal structure of a20 zf7 in complex with linear ubiquitin, form ii
Structure deposition date
2012-07-09
Thiol separation (Å)
4
Half-sphere exposure sum ?
69
Minimum pKa ?
6
% buried
44
Peptide accession
P21580
Residue number A
767
Residue number B
782
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 767 of Tumor necrosis factor alpha-induced protein 3
Cysteine 782 of Tumor necrosis factor alpha-induced protein 3
2eqg A 19 A 34
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 392 and 407 (19 and 34 respectively in this structure).
Details
Redox score ?
79
PDB code
2eqg
Structure name
solution structure of the first a20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3
Structure deposition date
2007-03-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
43
Minimum pKa ?
10
% buried
0
Peptide accession
P21580
Residue number A
392
Residue number B
407
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 392 of Tumor necrosis factor alpha-induced protein 3
Cysteine 407 of Tumor necrosis factor alpha-induced protein 3
3vux F 767 F 779
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 767 and 779.
Details
Redox score ?
79
PDB code
3vux
Structure name
crystal structure of a20 zf7 in complex with linear ubiquitin, form ii
Structure deposition date
2012-07-09
Thiol separation (Å)
4
Half-sphere exposure sum ?
64
Minimum pKa ?
6
% buried
34
Peptide accession
P21580
Residue number A
767
Residue number B
779
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 767 of Tumor necrosis factor alpha-induced protein 3
Cysteine 779 of Tumor necrosis factor alpha-induced protein 3
3vux G 762 G 779
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 762 and 779.
Details
Redox score ?
77
PDB code
3vux
Structure name
crystal structure of a20 zf7 in complex with linear ubiquitin, form ii
Structure deposition date
2012-07-09
Thiol separation (Å)
4
Half-sphere exposure sum ?
56
Minimum pKa ?
8
% buried
28
Peptide accession
P21580
Residue number A
762
Residue number B
779
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 762 of Tumor necrosis factor alpha-induced protein 3
Cysteine 779 of Tumor necrosis factor alpha-induced protein 3
3vux G 762 G 782
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 762 and 782.
Details
Redox score ?
76
PDB code
3vux
Structure name
crystal structure of a20 zf7 in complex with linear ubiquitin, form ii
Structure deposition date
2012-07-09
Thiol separation (Å)
4
Half-sphere exposure sum ?
63
Minimum pKa ?
8
% buried
42
Peptide accession
P21580
Residue number A
762
Residue number B
782
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 762 of Tumor necrosis factor alpha-induced protein 3
Cysteine 782 of Tumor necrosis factor alpha-induced protein 3
3oj3 O 607 O 627
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 607 and 627.
Details
Redox score ?
73
PDB code
3oj3
Structure name
crystal structure of the a20 znf4 and ubiquitin complex
Structure deposition date
2010-08-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
10
% buried
15
Peptide accession
P21580
Residue number A
607
Residue number B
627
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 607 of Tumor necrosis factor alpha-induced protein 3
Cysteine 627 of Tumor necrosis factor alpha-induced protein 3
3oj3 I 612 I 624
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 612 and 624.
Details
Redox score ?
64
PDB code
3oj3
Structure name
crystal structure of the a20 znf4 and ubiquitin complex
Structure deposition date
2010-08-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
68
Minimum pKa ?
14
% buried
nan
Peptide accession
P21580
Residue number A
612
Residue number B
624
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 612 of Tumor necrosis factor alpha-induced protein 3
Cysteine 624 of Tumor necrosis factor alpha-induced protein 3
3vuy F 775 F 779
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 775 and 779.
Details
Redox score ?
61
PDB code
3vuy
Structure name
crystal structure of a20 zf7 in complex with linear tetraubiquitin
Structure deposition date
2012-07-09
Thiol separation (Å)
7
Half-sphere exposure sum ?
50
Minimum pKa ?
9
% buried
14
Peptide accession
P21580
Residue number A
775
Residue number B
779
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 775 of Tumor necrosis factor alpha-induced protein 3
Cysteine 779 of Tumor necrosis factor alpha-induced protein 3
3vuw E 779 E 782
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 779 and 782. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
60
PDB code
3vuw
Structure name
crystal structure of a20 zf7 in complex with linear ubiquitin, form i
Structure deposition date
2012-07-09
Thiol separation (Å)
4
Half-sphere exposure sum ?
80
Minimum pKa ?
15
% buried
74
Peptide accession
P21580
Residue number A
779
Residue number B
782
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 779 of Tumor necrosis factor alpha-induced protein 3
Cysteine 782 of Tumor necrosis factor alpha-induced protein 3
3oj3 I 624 I 627
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 624 and 627. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
3oj3
Structure name
crystal structure of the a20 znf4 and ubiquitin complex
Structure deposition date
2010-08-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
79
Minimum pKa ?
14
% buried
71
Peptide accession
P21580
Residue number A
624
Residue number B
627
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 624 of Tumor necrosis factor alpha-induced protein 3
Cysteine 627 of Tumor necrosis factor alpha-induced protein 3
3vuy D 762 D 775
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 762 and 775. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
57
PDB code
3vuy
Structure name
crystal structure of a20 zf7 in complex with linear tetraubiquitin
Structure deposition date
2012-07-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
47
Minimum pKa ?
8
% buried
12
Peptide accession
P21580
Residue number A
762
Residue number B
775
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 762 of Tumor necrosis factor alpha-induced protein 3
Cysteine 775 of Tumor necrosis factor alpha-induced protein 3
3vux G 775 G 782
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 775 and 782. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
3vux
Structure name
crystal structure of a20 zf7 in complex with linear ubiquitin, form ii
Structure deposition date
2012-07-09
Thiol separation (Å)
10
Half-sphere exposure sum ?
57
Minimum pKa ?
9
% buried
28
Peptide accession
P21580
Residue number A
775
Residue number B
782
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 775 of Tumor necrosis factor alpha-induced protein 3
Cysteine 782 of Tumor necrosis factor alpha-induced protein 3
3dkb D 3200 D 3243
A redox-regulated disulphide may form within Tumor necrosis factor alpha-induced protein 3 between cysteines 200 and 243 (3200 and 3243 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
36
PDB code
3dkb
Structure name
crystal structure of a20, 2
Structure deposition date
2008-06-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
75
Minimum pKa ?
12
% buried
84
Peptide accession
P21580
Residue number A
200
Residue number B
243
Peptide name
Tumor necrosis factor alpha-induced protein 3
Ligandability
Cysteine 200 of Tumor necrosis factor alpha-induced protein 3
Cysteine 243 of Tumor necrosis factor alpha-induced protein 3
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