Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Intermolecular
Cysteine 305 of Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial and cysteine 93
Cysteine 305 of Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial and cysteine 113
Intramolecular
Cysteine 93 and cysteine 113
Cysteine 101 and cysteine 113
Cysteine 189 and cysteine 191
Cysteine 98 and cysteine 101
Cysteine 93 and cysteine 101
Cysteine 192 and cysteine 249
Cysteine 93 and cysteine 98
Cysteine 189 and cysteine 253
More...Cysteine 98 and cysteine 113
Cysteine 196 and cysteine 243
Cysteine 189 and cysteine 192
Cysteine 243 and cysteine 249
Cysteine 192 and cysteine 253
Cysteine 186 and cysteine 253
Cysteine 196 and cysteine 249
Cysteine 186 and cysteine 192
Cysteine 186 and cysteine 189
Cysteine 101 and cysteine 189
Cysteine 191 and cysteine 253
Cysteine 101 and cysteine 191
Cysteine 249 and cysteine 253
Cysteine 192 and cysteine 196
Cysteine 186 and cysteine 191
Cysteine 98 and cysteine 189
Cysteine 113 and cysteine 189
Cysteine 191 and cysteine 192
Cysteine 113 and cysteine 191
3ae5 A 263 B 65
A redox-regulated disulphide may form between cysteine 305 of Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial and cysteine 93 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (263 and 65 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
3ae5
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with 2-methyl-n-(3-isopropoxy-phenyl)-benzamide
Structure deposition date
2010-02-04
Thiol separation (Å)
8
Half-sphere exposure sum ?
82
Minimum pKa ?
3
% buried
100
Peptide A name
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Peptide B name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Peptide A accession
Q0QF01
Peptide B accession
Q007T0
Peptide A residue number
305
Peptide B residue number
93
Ligandability
Cysteine 305 of Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Cysteine 93 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3ae7 A 263 B 85
A redox-regulated disulphide may form between cysteine 305 of Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial and cysteine 113 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (263 and 85 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
3ae7
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with 2-iodo-n-(3-isopropoxy-phenyl)-benzamide
Structure deposition date
2010-02-04
Thiol separation (Å)
8
Half-sphere exposure sum ?
79
Minimum pKa ?
12
% buried
100
Peptide A name
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Peptide B name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Peptide A accession
Q0QF01
Peptide B accession
Q007T0
Peptide A residue number
305
Peptide B residue number
113
Ligandability
Cysteine 305 of Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Cysteine 113 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3sfd B 65 B 85
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 93 and 113 (65 and 85 respectively in this structure).
Details
Redox score ?
79
PDB code
3sfd
Structure name
crystal structure of porcine mitochondrial respiratory complex ii bound with oxaloacetate and pentachlorophenol
Structure deposition date
2011-06-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
77
Minimum pKa ?
3
% buried
100
Peptide accession
Q007T0
Residue number A
93
Residue number B
113
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 93 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 113 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3ae5 B 73 B 85
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 101 and 113 (73 and 85 respectively in this structure).
Details
Redox score ?
70
PDB code
3ae5
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with 2-methyl-n-(3-isopropoxy-phenyl)-benzamide
Structure deposition date
2010-02-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
83
Minimum pKa ?
9
% buried
100
Peptide accession
Q007T0
Residue number A
101
Residue number B
113
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 101 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 113 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3ae6 B 161 B 163
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 189 and 191 (161 and 163 respectively in this structure).
Details
Redox score ?
70
PDB code
3ae6
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with n-(3-isopropoxy-phenyl)-phthalamicacid
Structure deposition date
2010-02-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
90
Minimum pKa ?
8
% buried
100
Peptide accession
Q007T0
Residue number A
189
Residue number B
191
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 189 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 191 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
7kcm C 98 C 101
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 98 and 101.
Details
Redox score ?
68
PDB code
7kcm
Structure name
full-length human mitochondrial hsp90 (trap1) in complex with sdhb in the presence of amp-pnp
Structure deposition date
2020-10-06
Thiol separation (Å)
5
Half-sphere exposure sum ?
66
Minimum pKa ?
9
% buried
40
Peptide accession
P21912
Residue number A
98
Residue number B
101
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 98 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 101 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
7kcm C 93 C 101
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 93 and 101.
Details
Redox score ?
68
PDB code
7kcm
Structure name
full-length human mitochondrial hsp90 (trap1) in complex with sdhb in the presence of amp-pnp
Structure deposition date
2020-10-06
Thiol separation (Å)
6
Half-sphere exposure sum ?
49
Minimum pKa ?
7
% buried
24
Peptide accession
P21912
Residue number A
93
Residue number B
101
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 93 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 101 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3ae6 B 164 B 221
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 192 and 249 (164 and 221 respectively in this structure).
Details
Redox score ?
64
PDB code
3ae6
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with n-(3-isopropoxy-phenyl)-phthalamicacid
Structure deposition date
2010-02-04
Thiol separation (Å)
5
Half-sphere exposure sum ?
91
Minimum pKa ?
7
% buried
100
Peptide accession
Q007T0
Residue number A
192
Residue number B
249
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 192 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 249 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3aeb B 65 B 70
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 93 and 98 (65 and 70 respectively in this structure).
Details
Redox score ?
62
PDB code
3aeb
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with n-(3-phenoxy-phenyl)-2-trifluoromethyl-benzamide
Structure deposition date
2010-02-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
84
Minimum pKa ?
13
% buried
100
Peptide accession
Q007T0
Residue number A
93
Residue number B
98
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 93 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 98 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3sfe B 161 B 225
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 189 and 253 (161 and 225 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
60
PDB code
3sfe
Structure name
crystal structure of porcine mitochondrial respiratory complex ii bound with oxaloacetate and thiabendazole
Structure deposition date
2011-06-13
Thiol separation (Å)
6
Half-sphere exposure sum ?
80
Minimum pKa ?
8
% buried
94
Peptide accession
Q007T0
Residue number A
189
Residue number B
253
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 189 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 253 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
7kcm C 98 C 113
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 98 and 113. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
7kcm
Structure name
full-length human mitochondrial hsp90 (trap1) in complex with sdhb in the presence of amp-pnp
Structure deposition date
2020-10-06
Thiol separation (Å)
6
Half-sphere exposure sum ?
63
Minimum pKa ?
9
% buried
32
Peptide accession
P21912
Residue number A
98
Residue number B
113
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 98 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 113 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3aef B 168 B 215
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 196 and 243 (168 and 215 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
56
PDB code
3aef
Structure name
crystal structure of porcine heart mitochondrial complex ii with an empty quinone-binding pocket
Structure deposition date
2010-02-04
Thiol separation (Å)
6
Half-sphere exposure sum ?
82
Minimum pKa ?
10
% buried
100
Peptide accession
Q007T0
Residue number A
196
Residue number B
243
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 196 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 243 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3aed B 161 B 164
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 189 and 192 (161 and 164 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
3aed
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with 2-iodo-n-phenyl-benzamide
Structure deposition date
2010-02-04
Thiol separation (Å)
6
Half-sphere exposure sum ?
88
Minimum pKa ?
8
% buried
100
Peptide accession
Q007T0
Residue number A
189
Residue number B
192
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 189 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 192 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3ae4 B 215 B 221
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 243 and 249 (215 and 221 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
3ae4
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with 2-iodo-n-methyl-benzamide
Structure deposition date
2010-02-04
Thiol separation (Å)
6
Half-sphere exposure sum ?
86
Minimum pKa ?
10
% buried
100
Peptide accession
Q007T0
Residue number A
243
Residue number B
249
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 243 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 249 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3aec B 164 B 225
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 192 and 253 (164 and 225 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
3aec
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with 2-iodo-n-(1-methylethyl)-benzamid
Structure deposition date
2010-02-04
Thiol separation (Å)
6
Half-sphere exposure sum ?
85
Minimum pKa ?
11
% buried
92
Peptide accession
Q007T0
Residue number A
192
Residue number B
253
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 192 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 253 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3ae2 B 158 B 225
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 186 and 253 (158 and 225 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
3ae2
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with 2-hydroxy-n-phenyl-benzamide
Structure deposition date
2010-02-04
Thiol separation (Å)
7
Half-sphere exposure sum ?
77
Minimum pKa ?
12
% buried
94
Peptide accession
Q007T0
Residue number A
186
Residue number B
253
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 186 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 253 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3aeg B 168 B 221
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 196 and 249 (168 and 221 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
3aeg
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with n-biphenyl-3-yl-2-iodo-benzamide
Structure deposition date
2010-02-04
Thiol separation (Å)
6
Half-sphere exposure sum ?
86
Minimum pKa ?
13
% buried
100
Peptide accession
Q007T0
Residue number A
196
Residue number B
249
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 196 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 249 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3aed B 158 B 164
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 186 and 192 (158 and 164 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
3aed
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with 2-iodo-n-phenyl-benzamide
Structure deposition date
2010-02-04
Thiol separation (Å)
6
Half-sphere exposure sum ?
84
Minimum pKa ?
13
% buried
100
Peptide accession
Q007T0
Residue number A
186
Residue number B
192
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 186 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 192 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3aee B 158 B 161
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 186 and 189 (158 and 161 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
3aee
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with atpenin a5
Structure deposition date
2010-02-04
Thiol separation (Å)
7
Half-sphere exposure sum ?
79
Minimum pKa ?
13
% buried
100
Peptide accession
Q007T0
Residue number A
186
Residue number B
189
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 186 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 189 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3ae2 B 73 B 161
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 101 and 189 (73 and 161 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
3ae2
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with 2-hydroxy-n-phenyl-benzamide
Structure deposition date
2010-02-04
Thiol separation (Å)
9
Half-sphere exposure sum ?
85
Minimum pKa ?
8
% buried
100
Peptide accession
Q007T0
Residue number A
101
Residue number B
189
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 101 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 189 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3ae7 B 163 B 225
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 191 and 253 (163 and 225 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
3ae7
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with 2-iodo-n-(3-isopropoxy-phenyl)-benzamide
Structure deposition date
2010-02-04
Thiol separation (Å)
8
Half-sphere exposure sum ?
85
Minimum pKa ?
11
% buried
93
Peptide accession
Q007T0
Residue number A
191
Residue number B
253
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 191 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 253 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3ae4 B 73 B 163
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 101 and 191 (73 and 163 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
3ae4
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with 2-iodo-n-methyl-benzamide
Structure deposition date
2010-02-04
Thiol separation (Å)
9
Half-sphere exposure sum ?
89
Minimum pKa ?
9
% buried
100
Peptide accession
Q007T0
Residue number A
101
Residue number B
191
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 101 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 191 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3aed B 221 B 225
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 249 and 253 (221 and 225 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
36
PDB code
3aed
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with 2-iodo-n-phenyl-benzamide
Structure deposition date
2010-02-04
Thiol separation (Å)
9
Half-sphere exposure sum ?
84
Minimum pKa ?
12
% buried
93
Peptide accession
Q007T0
Residue number A
249
Residue number B
253
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 249 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 253 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3sfd B 164 B 168
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 192 and 196 (164 and 168 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
30
PDB code
3sfd
Structure name
crystal structure of porcine mitochondrial respiratory complex ii bound with oxaloacetate and pentachlorophenol
Structure deposition date
2011-06-13
Thiol separation (Å)
9
Half-sphere exposure sum ?
90
Minimum pKa ?
13
% buried
100
Peptide accession
Q007T0
Residue number A
192
Residue number B
196
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 192 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 196 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3ae8 B 158 B 163
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 186 and 191 (158 and 163 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
26
PDB code
3ae8
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with n-(3-isopropoxy-phenyl)-2-trifluoromethylbenzamide
Structure deposition date
2010-02-04
Thiol separation (Å)
10
Half-sphere exposure sum ?
82
Minimum pKa ?
13
% buried
100
Peptide accession
Q007T0
Residue number A
186
Residue number B
191
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 186 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 191 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3aee B 70 B 161
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 98 and 189 (70 and 161 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
22
PDB code
3aee
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with atpenin a5
Structure deposition date
2010-02-04
Thiol separation (Å)
9
Half-sphere exposure sum ?
87
Minimum pKa ?
17
% buried
100
Peptide accession
Q007T0
Residue number A
98
Residue number B
189
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 98 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 189 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3aee B 85 B 161
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 113 and 189 (85 and 161 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
20
PDB code
3aee
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with atpenin a5
Structure deposition date
2010-02-04
Thiol separation (Å)
9
Half-sphere exposure sum ?
78
Minimum pKa ?
18
% buried
100
Peptide accession
Q007T0
Residue number A
113
Residue number B
189
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 113 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 189 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3ae6 B 163 B 164
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 191 and 192 (163 and 164 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
16
PDB code
3ae6
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with n-(3-isopropoxy-phenyl)-phthalamicacid
Structure deposition date
2010-02-04
Thiol separation (Å)
8
Half-sphere exposure sum ?
93
Minimum pKa ?
19
% buried
100
Peptide accession
Q007T0
Residue number A
191
Residue number B
192
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 191 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 192 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
3aeg B 85 B 163
A redox-regulated disulphide may form within Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial between cysteines 113 and 191 (85 and 163 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
12
PDB code
3aeg
Structure name
crystal structure of porcine heart mitochondrial complex ii bound with n-biphenyl-3-yl-2-iodo-benzamide
Structure deposition date
2010-02-04
Thiol separation (Å)
10
Half-sphere exposure sum ?
82
Minimum pKa ?
19
% buried
100
Peptide accession
Q007T0
Residue number A
113
Residue number B
191
Peptide name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligandability
Cysteine 113 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Cysteine 191 of Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
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