ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Fibroblast growth factor receptor 3

Intramolecular
Cysteine 176 and cysteine 228
Cysteine 275 and cysteine 339
A redox-regulated disulphide may form within Fibroblast growth factor receptor 3 between cysteines 176 and 228.

Details

Redox score ?
79
PDB code
1ry7
Structure name
crystal structure of the 3 ig form of fgfr3c in complex with fgf1
Structure deposition date
2003-12-19
Thiol separation (Å)
3
Half-sphere exposure sum ?
78
Minimum pKa ?
7
% buried
62
Peptide accession
P22607
Residue number A
176
Residue number B
228
Peptide name
Fibroblast growth factor receptor 3

Ligandability

Cysteine 176 of Fibroblast growth factor receptor 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 228 of Fibroblast growth factor receptor 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Fibroblast growth factor receptor 3 between cysteines 275 and 339.

Details

Redox score ?
75
PDB code
1ry7
Structure name
crystal structure of the 3 ig form of fgfr3c in complex with fgf1
Structure deposition date
2003-12-19
Thiol separation (Å)
3
Half-sphere exposure sum ?
82
Minimum pKa ?
9
% buried
92
Peptide accession
P22607
Residue number A
275
Residue number B
339
Peptide name
Fibroblast growth factor receptor 3

Ligandability

Cysteine 275 of Fibroblast growth factor receptor 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 339 of Fibroblast growth factor receptor 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: