a tool for identifying drug-targetable redox-active disulphides

Carbonic anhydrase 6

Intramolecular

Cysteine 42 and cysteine 224

A redox-regulated disulphide may form within Carbonic anhydrase 6 between cysteines 42 and 224.

Details

Redox score ?

84

PDB code

Structure name

crystal structure of human carbonic anhydrase vi

Structure deposition date

2008-11-27

Thiol separation (Å)

2

Half-sphere exposure sum ?

63

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

42

Residue number B

224

Peptide name

Carbonic anhydrase 6

Ligandability

Cysteine 42 of Carbonic anhydrase 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 224 of Carbonic anhydrase 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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