ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Ribosomal protein S6 kinase beta-1

Intramolecular
Cysteine 240 and cysteine 254
A redox-regulated disulphide may form within Ribosomal protein S6 kinase beta-1 between cysteines 240 and 254 (217 and 231 respectively in this structure).

Details

Redox score ?
78
PDB code
4l42
Structure name
crystal structures of human p70s6k1-pif
Structure deposition date
2013-06-07
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
8
% buried
30
Peptide accession
Q7Z721
Residue number A
240
Residue number B
254
Peptide name
Ribosomal protein S6 kinase beta-1

Ligandability

Cysteine 240 of Ribosomal protein S6 kinase beta-1

Cysteine 254 of Ribosomal protein S6 kinase beta-1

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