ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Tumor necrosis factor ligand superfamily member 4

Intramolecular
Cysteine 70 and cysteine 163
Cysteine 97 and cysteine 181
A redox-regulated disulphide may form within Tumor necrosis factor ligand superfamily member 4 between cysteines 70 and 163.

Details

Redox score ?
87
PDB code
2hey
Structure name
crystal structure of murine ox40l bound to human ox40
Structure deposition date
2006-06-22
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P43488
Residue number A
70
Residue number B
163
Peptide name
Tumor necrosis factor ligand superfamily member 4

Ligandability

Cysteine 70 of Tumor necrosis factor ligand superfamily member 4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 163 of Tumor necrosis factor ligand superfamily member 4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Tumor necrosis factor ligand superfamily member 4 between cysteines 97 and 181.

Details

Redox score ?
84
PDB code
2hev
Structure name
crystal structure of the complex between ox40l and ox40
Structure deposition date
2006-06-22
Thiol separation (Å)
2
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P23510
Residue number A
97
Residue number B
181
Peptide name
Tumor necrosis factor ligand superfamily member 4

Ligandability

Cysteine 97 of Tumor necrosis factor ligand superfamily member 4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 181 of Tumor necrosis factor ligand superfamily member 4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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