ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Inositol-trisphosphate 3-kinase A

Intermolecular
Cysteine 342 and cysteine 342
A redox-regulated disulphide may form between two units of Inositol-trisphosphate 3-kinase A at cysteines 342 and 342.

Details

Redox score ?
66
PDB code
1w2c
Structure name
human inositol (1,4,5) trisphosphate 3-kinase complexed with mn2+/amppnp/ins(1,4,5)p3
Structure deposition date
2004-07-01
Thiol separation (Å)
5
Half-sphere exposure sum ?
60
Minimum pKa ?
9
% buried
42
Peptide A name
Inositol-trisphosphate 3-kinase A
Peptide B name
Inositol-trisphosphate 3-kinase A
Peptide A accession
P23677
Peptide B accession
P23677
Peptide A residue number
342
Peptide B residue number
342

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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