Thymidylate kinase

Intramolecular

A redox-regulated disulphide may form within Thymidylate kinase between cysteines 117 and 163. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

1e2g

Structure name

human thymidylate kinase complexed with adp, tdp and a magnesium-ion

Structure deposition date

2000-05-22

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

P23919

Residue number A

117

Residue number B

163

Peptide name

Thymidylate kinase

Ligandability

Cysteine 117 of Thymidylate kinase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Ligandable in the dataset of Backus et al.

Ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.