ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Immunoglobulin alpha Fc receptor

Intramolecular
Cysteine 49 and cysteine 100
Cysteine 146 and cysteine 193
A redox-regulated disulphide may form within Immunoglobulin alpha Fc receptor between cysteines 49 and 100 (28 and 79 respectively in this structure).

Details

Redox score ?
82
PDB code
1ow0
Structure name
crystal structure of human fcari bound to iga1-fc
Structure deposition date
2003-03-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
79
Minimum pKa ?
nan
% buried
nan
Peptide accession
P24071
Residue number A
49
Residue number B
100
Peptide name
Immunoglobulin alpha Fc receptor

Ligandability

Cysteine 49 of Immunoglobulin alpha Fc receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 100 of Immunoglobulin alpha Fc receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Immunoglobulin alpha Fc receptor between cysteines 146 and 193 (125 and 172 respectively in this structure).

Details

Redox score ?
81
PDB code
1ovz
Structure name
crystal structure of human fcari
Structure deposition date
2003-03-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
85
Minimum pKa ?
nan
% buried
nan
Peptide accession
P24071
Residue number A
146
Residue number B
193
Peptide name
Immunoglobulin alpha Fc receptor

Ligandability

Cysteine 146 of Immunoglobulin alpha Fc receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 193 of Immunoglobulin alpha Fc receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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