Rab proteins geranylgeranyltransferase component A 1
Intramolecular
Cysteine 27 and cysteine 596
Cysteine 490 and cysteine 496
Cysteine 596 and cysteine 602
Cysteine 385 and cysteine 388
Cysteine 441 and cysteine 561
Cysteine 27 and cysteine 388
Cysteine 403 and cysteine 413
Cysteine 27 and cysteine 602
Cysteine 383 and cysteine 385
Cysteine 388 and cysteine 602
Cysteine 27 and cysteine 572
1ltx R 27 R 596
A redox-regulated disulphide may form within Rab proteins geranylgeranyltransferase component A 1 between cysteines 27 and 596.
Details
Redox score ?
73
PDB code
1ltx
Structure name
structure of rab escort protein-1 in complex with rab geranylgeranyl transferase and isoprenoid
Structure deposition date
2002-05-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
71
Minimum pKa ?
7
% buried
66
Peptide accession
P37727
Residue number A
27
Residue number B
596
Peptide name
Rab proteins geranylgeranyltransferase component A 1
Ligandability
Cysteine 27 of Rab proteins geranylgeranyltransferase component A 1
Cysteine 596 of Rab proteins geranylgeranyltransferase component A 1
1vg9 E 490 E 496
A redox-regulated disulphide may form within Rab proteins geranylgeranyltransferase component A 1 between cysteines 490 and 496. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
1vg9
Structure name
the crystal structures of the rep-1 protein in complex with c- terminally truncated rab7 protein
Structure deposition date
2004-04-23
Thiol separation (Å)
7
Half-sphere exposure sum ?
80
Minimum pKa ?
11
% buried
89
Peptide accession
P37727
Residue number A
490
Residue number B
496
Peptide name
Rab proteins geranylgeranyltransferase component A 1
Ligandability
Cysteine 490 of Rab proteins geranylgeranyltransferase component A 1
Cysteine 496 of Rab proteins geranylgeranyltransferase component A 1
1vg0 A 596 A 602
A redox-regulated disulphide may form within Rab proteins geranylgeranyltransferase component A 1 between cysteines 596 and 602. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
1vg0
Structure name
the crystal structures of the rep-1 protein in complex with monoprenylated rab7 protein
Structure deposition date
2004-04-22
Thiol separation (Å)
10
Half-sphere exposure sum ?
64
Minimum pKa ?
7
% buried
72
Peptide accession
P37727
Residue number A
596
Residue number B
602
Peptide name
Rab proteins geranylgeranyltransferase component A 1
Ligandability
Cysteine 596 of Rab proteins geranylgeranyltransferase component A 1
Cysteine 602 of Rab proteins geranylgeranyltransferase component A 1
1vg0 A 385 A 388
A redox-regulated disulphide may form within Rab proteins geranylgeranyltransferase component A 1 between cysteines 385 and 388. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
1vg0
Structure name
the crystal structures of the rep-1 protein in complex with monoprenylated rab7 protein
Structure deposition date
2004-04-22
Thiol separation (Å)
7
Half-sphere exposure sum ?
96
Minimum pKa ?
12
% buried
100
Peptide accession
P37727
Residue number A
385
Residue number B
388
Peptide name
Rab proteins geranylgeranyltransferase component A 1
Ligandability
Cysteine 385 of Rab proteins geranylgeranyltransferase component A 1
Cysteine 388 of Rab proteins geranylgeranyltransferase component A 1
1vg9 E 441 E 561
A redox-regulated disulphide may form within Rab proteins geranylgeranyltransferase component A 1 between cysteines 441 and 561. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
1vg9
Structure name
the crystal structures of the rep-1 protein in complex with c- terminally truncated rab7 protein
Structure deposition date
2004-04-23
Thiol separation (Å)
10
Half-sphere exposure sum ?
46
Minimum pKa ?
9
% buried
26
Peptide accession
P37727
Residue number A
441
Residue number B
561
Peptide name
Rab proteins geranylgeranyltransferase component A 1
Ligandability
Cysteine 441 of Rab proteins geranylgeranyltransferase component A 1
Cysteine 561 of Rab proteins geranylgeranyltransferase component A 1
1ltx R 27 R 388
A redox-regulated disulphide may form within Rab proteins geranylgeranyltransferase component A 1 between cysteines 27 and 388. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
1ltx
Structure name
structure of rab escort protein-1 in complex with rab geranylgeranyl transferase and isoprenoid
Structure deposition date
2002-05-21
Thiol separation (Å)
8
Half-sphere exposure sum ?
80
Minimum pKa ?
11
% buried
88
Peptide accession
P37727
Residue number A
27
Residue number B
388
Peptide name
Rab proteins geranylgeranyltransferase component A 1
Ligandability
Cysteine 27 of Rab proteins geranylgeranyltransferase component A 1
Cysteine 388 of Rab proteins geranylgeranyltransferase component A 1
1vg9 G 403 G 413
A redox-regulated disulphide may form within Rab proteins geranylgeranyltransferase component A 1 between cysteines 403 and 413. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
36
PDB code
1vg9
Structure name
the crystal structures of the rep-1 protein in complex with c- terminally truncated rab7 protein
Structure deposition date
2004-04-23
Thiol separation (Å)
9
Half-sphere exposure sum ?
75
Minimum pKa ?
12
% buried
79
Peptide accession
P37727
Residue number A
403
Residue number B
413
Peptide name
Rab proteins geranylgeranyltransferase component A 1
Ligandability
Cysteine 403 of Rab proteins geranylgeranyltransferase component A 1
Cysteine 413 of Rab proteins geranylgeranyltransferase component A 1
1vg9 A 27 A 602
A redox-regulated disulphide may form within Rab proteins geranylgeranyltransferase component A 1 between cysteines 27 and 602. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
34
PDB code
1vg9
Structure name
the crystal structures of the rep-1 protein in complex with c- terminally truncated rab7 protein
Structure deposition date
2004-04-23
Thiol separation (Å)
9
Half-sphere exposure sum ?
84
Minimum pKa ?
12
% buried
100
Peptide accession
P37727
Residue number A
27
Residue number B
602
Peptide name
Rab proteins geranylgeranyltransferase component A 1
Ligandability
Cysteine 27 of Rab proteins geranylgeranyltransferase component A 1
Cysteine 602 of Rab proteins geranylgeranyltransferase component A 1
1ltx R 383 R 385
A redox-regulated disulphide may form within Rab proteins geranylgeranyltransferase component A 1 between cysteines 383 and 385. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
31
PDB code
1ltx
Structure name
structure of rab escort protein-1 in complex with rab geranylgeranyl transferase and isoprenoid
Structure deposition date
2002-05-21
Thiol separation (Å)
9
Half-sphere exposure sum ?
79
Minimum pKa ?
12
% buried
94
Peptide accession
P37727
Residue number A
383
Residue number B
385
Peptide name
Rab proteins geranylgeranyltransferase component A 1
Ligandability
Cysteine 383 of Rab proteins geranylgeranyltransferase component A 1
Cysteine 385 of Rab proteins geranylgeranyltransferase component A 1
1vg9 A 388 A 602
A redox-regulated disulphide may form within Rab proteins geranylgeranyltransferase component A 1 between cysteines 388 and 602. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
28
PDB code
1vg9
Structure name
the crystal structures of the rep-1 protein in complex with c- terminally truncated rab7 protein
Structure deposition date
2004-04-23
Thiol separation (Å)
10
Half-sphere exposure sum ?
83
Minimum pKa ?
12
% buried
100
Peptide accession
P37727
Residue number A
388
Residue number B
602
Peptide name
Rab proteins geranylgeranyltransferase component A 1
Ligandability
Cysteine 388 of Rab proteins geranylgeranyltransferase component A 1
Cysteine 602 of Rab proteins geranylgeranyltransferase component A 1
1vg9 C 27 C 572
A redox-regulated disulphide may form within Rab proteins geranylgeranyltransferase component A 1 between cysteines 27 and 572. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
21
PDB code
1vg9
Structure name
the crystal structures of the rep-1 protein in complex with c- terminally truncated rab7 protein
Structure deposition date
2004-04-23
Thiol separation (Å)
10
Half-sphere exposure sum ?
91
Minimum pKa ?
14
% buried
100
Peptide accession
P37727
Residue number A
27
Residue number B
572
Peptide name
Rab proteins geranylgeranyltransferase component A 1
Ligandability
Cysteine 27 of Rab proteins geranylgeranyltransferase component A 1
Cysteine 572 of Rab proteins geranylgeranyltransferase component A 1
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