Tumor necrosis factor receptor superfamily member 6
Intramolecular
Cysteine 129 and cysteine 104
Cysteine 146 and cysteine 157
Cysteine 104 and cysteine 119
Cysteine 85 and cysteine 101
Cysteine 135 and cysteine 140
Cysteine 107 and cysteine 127
Cysteine 129 and cysteine 143
Cysteine 59 and cysteine 73
Cysteine 63 and cysteine 82
Cysteine 140 and cysteine 143
More...Cysteine 129 and cysteine 140
Cysteine 135 and cysteine 143
Cysteine 129 and cysteine 135
Cysteine 129 and cysteine 146
Cysteine 129 and cysteine 157
Cysteine 85 and cysteine 104
Cysteine 85 and cysteine 119
Cysteine 59 and cysteine 63
Cysteine 127 and cysteine 129
Cysteine 63 and cysteine 73
Cysteine 73 and cysteine 82
Cysteine 101 and cysteine 104
Cysteine 107 and cysteine 129
Cysteine 143 and cysteine 146
Cysteine 127 and cysteine 143
Cysteine 59 and cysteine 82
Cysteine 143 and cysteine 157
Cysteine 107 and cysteine 119
Cysteine 119 and cysteine 127
Cysteine 127 and cysteine 140
Cysteine 101 and cysteine 119
Cysteine 107 and cysteine 143
Cysteine 63 and cysteine 101
Cysteine 63 and cysteine 85
3thm F 113 F 127
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 129 and 104 (113 and 127 respectively in this structure).
Details
Redox score ?
94
PDB code
3thm
Structure name
crystal structure of fas receptor extracellular domain in complex with fab ep6b_b01
Structure deposition date
2011-08-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
129
Residue number B
104
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 129 of Tumor necrosis factor receptor superfamily member 6
Cysteine 104 of Tumor necrosis factor receptor superfamily member 6
3tje F 130 F 141
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 146 and 157 (130 and 141 respectively in this structure).
Details
Redox score ?
92
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
146
Residue number B
157
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 146 of Tumor necrosis factor receptor superfamily member 6
Cysteine 157 of Tumor necrosis factor receptor superfamily member 6
3tje F 88 F 103
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 104 and 119 (88 and 103 respectively in this structure).
Details
Redox score ?
89
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
104
Residue number B
119
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 104 of Tumor necrosis factor receptor superfamily member 6
Cysteine 119 of Tumor necrosis factor receptor superfamily member 6
3tje F 69 F 85
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 85 and 101 (69 and 85 respectively in this structure).
Details
Redox score ?
89
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
85
Residue number B
101
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 85 of Tumor necrosis factor receptor superfamily member 6
Cysteine 101 of Tumor necrosis factor receptor superfamily member 6
3tje F 119 F 124
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 135 and 140 (119 and 124 respectively in this structure).
Details
Redox score ?
88
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
135
Residue number B
140
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 135 of Tumor necrosis factor receptor superfamily member 6
Cysteine 140 of Tumor necrosis factor receptor superfamily member 6
3tje F 91 F 111
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 107 and 127 (91 and 111 respectively in this structure).
Details
Redox score ?
88
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
107
Residue number B
127
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 107 of Tumor necrosis factor receptor superfamily member 6
Cysteine 127 of Tumor necrosis factor receptor superfamily member 6
3tje F 113 F 127
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 129 and 143 (113 and 127 respectively in this structure).
Details
Redox score ?
86
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
129
Residue number B
143
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 129 of Tumor necrosis factor receptor superfamily member 6
Cysteine 143 of Tumor necrosis factor receptor superfamily member 6
3thm F 43 F 57
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 59 and 73 (43 and 57 respectively in this structure).
Details
Redox score ?
84
PDB code
3thm
Structure name
crystal structure of fas receptor extracellular domain in complex with fab ep6b_b01
Structure deposition date
2011-08-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
59
Residue number B
73
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 59 of Tumor necrosis factor receptor superfamily member 6
Cysteine 73 of Tumor necrosis factor receptor superfamily member 6
3tje F 47 F 66
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 63 and 82 (47 and 66 respectively in this structure).
Details
Redox score ?
83
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
2
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
63
Residue number B
82
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 63 of Tumor necrosis factor receptor superfamily member 6
Cysteine 82 of Tumor necrosis factor receptor superfamily member 6
3tje F 124 F 127
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 140 and 143 (124 and 127 respectively in this structure).
Details
Redox score ?
71
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
5
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
140
Residue number B
143
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 140 of Tumor necrosis factor receptor superfamily member 6
Cysteine 143 of Tumor necrosis factor receptor superfamily member 6
3tje F 113 F 124
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 129 and 140 (113 and 124 respectively in this structure).
Details
Redox score ?
67
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
6
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
129
Residue number B
140
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 129 of Tumor necrosis factor receptor superfamily member 6
Cysteine 140 of Tumor necrosis factor receptor superfamily member 6
3tje F 119 F 127
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 135 and 143 (119 and 127 respectively in this structure).
Details
Redox score ?
67
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
5
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
135
Residue number B
143
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 135 of Tumor necrosis factor receptor superfamily member 6
Cysteine 143 of Tumor necrosis factor receptor superfamily member 6
3tje F 113 F 119
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 129 and 135 (113 and 119 respectively in this structure).
Details
Redox score ?
64
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
6
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
129
Residue number B
135
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 129 of Tumor necrosis factor receptor superfamily member 6
Cysteine 135 of Tumor necrosis factor receptor superfamily member 6
3tje F 113 F 130
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 129 and 146 (113 and 130 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
8
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
129
Residue number B
146
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 129 of Tumor necrosis factor receptor superfamily member 6
Cysteine 146 of Tumor necrosis factor receptor superfamily member 6
3tje F 113 F 141
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 129 and 157 (113 and 141 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
8
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
129
Residue number B
157
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 129 of Tumor necrosis factor receptor superfamily member 6
Cysteine 157 of Tumor necrosis factor receptor superfamily member 6
3tje F 69 F 88
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 85 and 104 (69 and 88 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
8
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
85
Residue number B
104
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 85 of Tumor necrosis factor receptor superfamily member 6
Cysteine 104 of Tumor necrosis factor receptor superfamily member 6
3tje F 69 F 103
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 85 and 119 (69 and 103 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
85
Residue number B
119
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 85 of Tumor necrosis factor receptor superfamily member 6
Cysteine 119 of Tumor necrosis factor receptor superfamily member 6
3tje F 43 F 47
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 59 and 63 (43 and 47 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
7
Half-sphere exposure sum ?
83
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
59
Residue number B
63
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 59 of Tumor necrosis factor receptor superfamily member 6
Cysteine 63 of Tumor necrosis factor receptor superfamily member 6
3thm F 111 F 113
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 127 and 129 (111 and 113 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
3thm
Structure name
crystal structure of fas receptor extracellular domain in complex with fab ep6b_b01
Structure deposition date
2011-08-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
127
Residue number B
129
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 127 of Tumor necrosis factor receptor superfamily member 6
Cysteine 129 of Tumor necrosis factor receptor superfamily member 6
3thm F 47 F 57
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 63 and 73 (47 and 57 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
3thm
Structure name
crystal structure of fas receptor extracellular domain in complex with fab ep6b_b01
Structure deposition date
2011-08-19
Thiol separation (Å)
8
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
63
Residue number B
73
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 63 of Tumor necrosis factor receptor superfamily member 6
Cysteine 73 of Tumor necrosis factor receptor superfamily member 6
3thm F 57 F 66
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 73 and 82 (57 and 66 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
3thm
Structure name
crystal structure of fas receptor extracellular domain in complex with fab ep6b_b01
Structure deposition date
2011-08-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
73
Residue number B
82
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 73 of Tumor necrosis factor receptor superfamily member 6
Cysteine 82 of Tumor necrosis factor receptor superfamily member 6
3tje F 85 F 88
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 101 and 104 (85 and 88 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
101
Residue number B
104
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 101 of Tumor necrosis factor receptor superfamily member 6
Cysteine 104 of Tumor necrosis factor receptor superfamily member 6
3thm F 91 F 113
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 107 and 129 (91 and 113 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
3thm
Structure name
crystal structure of fas receptor extracellular domain in complex with fab ep6b_b01
Structure deposition date
2011-08-19
Thiol separation (Å)
10
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
107
Residue number B
129
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 107 of Tumor necrosis factor receptor superfamily member 6
Cysteine 129 of Tumor necrosis factor receptor superfamily member 6
3tje F 127 F 130
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 143 and 146 (127 and 130 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
143
Residue number B
146
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 143 of Tumor necrosis factor receptor superfamily member 6
Cysteine 146 of Tumor necrosis factor receptor superfamily member 6
3tje F 111 F 127
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 127 and 143 (111 and 127 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
127
Residue number B
143
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 127 of Tumor necrosis factor receptor superfamily member 6
Cysteine 143 of Tumor necrosis factor receptor superfamily member 6
3thm F 43 F 66
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 59 and 82 (43 and 66 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
3thm
Structure name
crystal structure of fas receptor extracellular domain in complex with fab ep6b_b01
Structure deposition date
2011-08-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
59
Residue number B
82
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 59 of Tumor necrosis factor receptor superfamily member 6
Cysteine 82 of Tumor necrosis factor receptor superfamily member 6
3tje F 127 F 141
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 143 and 157 (127 and 141 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
10
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
143
Residue number B
157
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 143 of Tumor necrosis factor receptor superfamily member 6
Cysteine 157 of Tumor necrosis factor receptor superfamily member 6
3thm F 91 F 103
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 107 and 119 (91 and 103 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
3thm
Structure name
crystal structure of fas receptor extracellular domain in complex with fab ep6b_b01
Structure deposition date
2011-08-19
Thiol separation (Å)
10
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
107
Residue number B
119
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 107 of Tumor necrosis factor receptor superfamily member 6
Cysteine 119 of Tumor necrosis factor receptor superfamily member 6
3thm F 103 F 111
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 119 and 127 (103 and 111 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
3thm
Structure name
crystal structure of fas receptor extracellular domain in complex with fab ep6b_b01
Structure deposition date
2011-08-19
Thiol separation (Å)
10
Half-sphere exposure sum ?
47
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
119
Residue number B
127
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 119 of Tumor necrosis factor receptor superfamily member 6
Cysteine 127 of Tumor necrosis factor receptor superfamily member 6
3tje F 111 F 124
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 127 and 140 (111 and 124 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
10
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
127
Residue number B
140
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 127 of Tumor necrosis factor receptor superfamily member 6
Cysteine 140 of Tumor necrosis factor receptor superfamily member 6
3tje F 85 F 103
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 101 and 119 (85 and 103 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
10
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
101
Residue number B
119
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 101 of Tumor necrosis factor receptor superfamily member 6
Cysteine 119 of Tumor necrosis factor receptor superfamily member 6
3tje F 91 F 127
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 107 and 143 (91 and 127 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
3tje
Structure name
crystal structure of fas receptor extracellular domain in complex with fab e09
Structure deposition date
2011-08-24
Thiol separation (Å)
10
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
107
Residue number B
143
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 107 of Tumor necrosis factor receptor superfamily member 6
Cysteine 143 of Tumor necrosis factor receptor superfamily member 6
3thm F 47 F 85
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 63 and 101 (47 and 85 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
3thm
Structure name
crystal structure of fas receptor extracellular domain in complex with fab ep6b_b01
Structure deposition date
2011-08-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
63
Residue number B
101
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 63 of Tumor necrosis factor receptor superfamily member 6
Cysteine 101 of Tumor necrosis factor receptor superfamily member 6
3thm F 47 F 69
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 6 between cysteines 63 and 85 (47 and 69 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
3thm
Structure name
crystal structure of fas receptor extracellular domain in complex with fab ep6b_b01
Structure deposition date
2011-08-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
P25445
Residue number A
63
Residue number B
85
Peptide name
Tumor necrosis factor receptor superfamily member 6
Ligandability
Cysteine 63 of Tumor necrosis factor receptor superfamily member 6
Cysteine 85 of Tumor necrosis factor receptor superfamily member 6
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