Integrin beta-8
Intramolecular
Cysteine 439 and cysteine 767
Cysteine 439 and cysteine 467
Cysteine 94 and cysteine 218
Cysteine 211 and cysteine 218
Cysteine 266 and cysteine 307
Cysteine 407 and cysteine 419
6om1 B 397 B 425
A redox-regulated disulphide may form within Integrin beta-8 between cysteines 439 and 767 (397 and 425 respectively in this structure).
Details
Redox score ?
94
PDB code
6om1
Structure name
crystal structure of an atypical integrin
Structure deposition date
2019-04-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26012
Residue number A
439
Residue number B
767
Peptide name
Integrin beta-8
Ligandability
Cysteine 439 of Integrin beta-8
Cysteine 767 of Integrin beta-8
6ujb B 397 B 425
A redox-regulated disulphide may form within Integrin beta-8 between cysteines 439 and 467 (397 and 425 respectively in this structure).
Details
Redox score ?
91
PDB code
6ujb
Structure name
integrin alpha-v beta-8 in complex with the fabs c6d4 and 11d12v2
Structure deposition date
2019-10-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26012
Residue number A
439
Residue number B
467
Peptide name
Integrin beta-8
Ligandability
Cysteine 439 of Integrin beta-8
Cysteine 467 of Integrin beta-8
6om1 F 169 F 176
A redox-regulated disulphide may form within Integrin beta-8 between cysteines 94 and 218 (169 and 176 respectively in this structure).
Details
Redox score ?
88
PDB code
6om1
Structure name
crystal structure of an atypical integrin
Structure deposition date
2019-04-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
nan
Minimum pKa ?
9
% buried
14
Peptide accession
P26012
Residue number A
94
Residue number B
218
Peptide name
Integrin beta-8
Ligandability
Cysteine 94 of Integrin beta-8
Cysteine 218 of Integrin beta-8
6om2 B 169 B 176
A redox-regulated disulphide may form within Integrin beta-8 between cysteines 211 and 218 (169 and 176 respectively in this structure).
Details
Redox score ?
86
PDB code
6om2
Structure name
crystal structure of atypical integrin alphav beta8 with protgf-beta1 ligand peptide
Structure deposition date
2019-04-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26012
Residue number A
211
Residue number B
218
Peptide name
Integrin beta-8
Ligandability
Cysteine 211 of Integrin beta-8
Cysteine 218 of Integrin beta-8
6om1 H 224 H 265
A redox-regulated disulphide may form within Integrin beta-8 between cysteines 266 and 307 (224 and 265 respectively in this structure).
Details
Redox score ?
86
PDB code
6om1
Structure name
crystal structure of an atypical integrin
Structure deposition date
2019-04-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26012
Residue number A
266
Residue number B
307
Peptide name
Integrin beta-8
Ligandability
Cysteine 266 of Integrin beta-8
Cysteine 307 of Integrin beta-8
6om1 B 365 B 377
A redox-regulated disulphide may form within Integrin beta-8 between cysteines 407 and 419 (365 and 377 respectively in this structure).
Details
Redox score ?
84
PDB code
6om1
Structure name
crystal structure of an atypical integrin
Structure deposition date
2019-04-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26012
Residue number A
407
Residue number B
419
Peptide name
Integrin beta-8
Ligandability
Cysteine 407 of Integrin beta-8
Cysteine 419 of Integrin beta-8
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