CD27 antigen
Intramolecular
Cysteine 106 and cysteine 120
Cysteine 87 and cysteine 104
Cysteine 43 and cysteine 62
Cysteine 40 and cysteine 53
Cysteine 84 and cysteine 96
Cysteine 27 and cysteine 39
Cysteine 112 and cysteine 117
Cysteine 65 and cysteine 81
Cysteine 106 and cysteine 112
Cysteine 106 and cysteine 117
More...Cysteine 112 and cysteine 120
Cysteine 117 and cysteine 120
Cysteine 84 and cysteine 104
Cysteine 65 and cysteine 84
Cysteine 84 and cysteine 87
Cysteine 104 and cysteine 117
Cysteine 104 and cysteine 112
Cysteine 27 and cysteine 40
Cysteine 65 and cysteine 96
Cysteine 104 and cysteine 120
Cysteine 81 and cysteine 84
Cysteine 43 and cysteine 81
Cysteine 104 and cysteine 106
Cysteine 87 and cysteine 117
Cysteine 43 and cysteine 65
Cysteine 96 and cysteine 104
Cysteine 39 and cysteine 40
Cysteine 27 and cysteine 53
Cysteine 87 and cysteine 106
Cysteine 87 and cysteine 120
Cysteine 53 and cysteine 62
Cysteine 39 and cysteine 53
Cysteine 62 and cysteine 65
Cysteine 87 and cysteine 112
Cysteine 62 and cysteine 81
Cysteine 40 and cysteine 62
Cysteine 87 and cysteine 96
Cysteine 81 and cysteine 96
Cysteine 40 and cysteine 43
8ds5 A 106 A 120
A redox-regulated disulphide may form within CD27 antigen between cysteines 106 and 120.
Details
Redox score ?
90
PDB code
8ds5
Structure name
x-ray structure of the mk5890 fab - cd27 antibody-antigen complex
Structure deposition date
2022-07-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
47
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
106
Residue number B
120
Peptide name
CD27 antigen
Ligandability
Cysteine 106 of CD27 antigen
Cysteine 120 of CD27 antigen
8ds5 A 87 A 104
A redox-regulated disulphide may form within CD27 antigen between cysteines 87 and 104.
Details
Redox score ?
89
PDB code
8ds5
Structure name
x-ray structure of the mk5890 fab - cd27 antibody-antigen complex
Structure deposition date
2022-07-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
87
Residue number B
104
Peptide name
CD27 antigen
Ligandability
Cysteine 87 of CD27 antigen
Cysteine 104 of CD27 antigen
8ds5 A 43 A 62
A redox-regulated disulphide may form within CD27 antigen between cysteines 43 and 62.
Details
Redox score ?
87
PDB code
8ds5
Structure name
x-ray structure of the mk5890 fab - cd27 antibody-antigen complex
Structure deposition date
2022-07-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
43
Residue number B
62
Peptide name
CD27 antigen
Ligandability
Cysteine 43 of CD27 antigen
Cysteine 62 of CD27 antigen
5tlk Y 20 Y 33
A redox-regulated disulphide may form within CD27 antigen between cysteines 40 and 53 (20 and 33 respectively in this structure).
Details
Redox score ?
85
PDB code
5tlk
Structure name
complex between human cd27 and fab fragments of antibodies m2177 and h2191
Structure deposition date
2016-10-11
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
40
Residue number B
53
Peptide name
CD27 antigen
Ligandability
Cysteine 40 of CD27 antigen
Cysteine 53 of CD27 antigen
7kx0 F 84 F 96
A redox-regulated disulphide may form within CD27 antigen between cysteines 84 and 96.
Details
Redox score ?
84
PDB code
7kx0
Structure name
crystal structure of the cd27:cd70 co-stimulatory complex
Structure deposition date
2020-12-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
84
Residue number B
96
Peptide name
CD27 antigen
Ligandability
Cysteine 84 of CD27 antigen
Cysteine 96 of CD27 antigen
5tlj X 7 X 19
A redox-regulated disulphide may form within CD27 antigen between cysteines 27 and 39 (7 and 19 respectively in this structure).
Details
Redox score ?
84
PDB code
5tlj
Structure name
complex between human cd27 and fab fragments of antibodies m2177 and m2191
Structure deposition date
2016-10-11
Thiol separation (Å)
2
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
27
Residue number B
39
Peptide name
CD27 antigen
Ligandability
Cysteine 27 of CD27 antigen
Cysteine 39 of CD27 antigen
7kx0 D 112 D 117
A redox-regulated disulphide may form within CD27 antigen between cysteines 112 and 117.
Details
Redox score ?
84
PDB code
7kx0
Structure name
crystal structure of the cd27:cd70 co-stimulatory complex
Structure deposition date
2020-12-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
112
Residue number B
117
Peptide name
CD27 antigen
Ligandability
Cysteine 112 of CD27 antigen
Cysteine 117 of CD27 antigen
5tlj X 45 X 61
A redox-regulated disulphide may form within CD27 antigen between cysteines 65 and 81 (45 and 61 respectively in this structure).
Details
Redox score ?
83
PDB code
5tlj
Structure name
complex between human cd27 and fab fragments of antibodies m2177 and m2191
Structure deposition date
2016-10-11
Thiol separation (Å)
2
Half-sphere exposure sum ?
86
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
65
Residue number B
81
Peptide name
CD27 antigen
Ligandability
Cysteine 65 of CD27 antigen
Cysteine 81 of CD27 antigen
7kx0 F 106 F 112
A redox-regulated disulphide may form within CD27 antigen between cysteines 106 and 112.
Details
Redox score ?
79
PDB code
7kx0
Structure name
crystal structure of the cd27:cd70 co-stimulatory complex
Structure deposition date
2020-12-02
Thiol separation (Å)
3
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
106
Residue number B
112
Peptide name
CD27 antigen
Ligandability
Cysteine 106 of CD27 antigen
Cysteine 112 of CD27 antigen
5tl5 A 86 A 97
A redox-regulated disulphide may form within CD27 antigen between cysteines 106 and 117 (86 and 97 respectively in this structure).
Details
Redox score ?
71
PDB code
5tl5
Structure name
complex between human cd27 and antibody m2177
Structure deposition date
2016-10-10
Thiol separation (Å)
5
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
106
Residue number B
117
Peptide name
CD27 antigen
Ligandability
Cysteine 106 of CD27 antigen
Cysteine 117 of CD27 antigen
8ds5 A 112 A 120
A redox-regulated disulphide may form within CD27 antigen between cysteines 112 and 120.
Details
Redox score ?
71
PDB code
8ds5
Structure name
x-ray structure of the mk5890 fab - cd27 antibody-antigen complex
Structure deposition date
2022-07-21
Thiol separation (Å)
5
Half-sphere exposure sum ?
44
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
112
Residue number B
120
Peptide name
CD27 antigen
Ligandability
Cysteine 112 of CD27 antigen
Cysteine 120 of CD27 antigen
7kx0 E 117 E 120
A redox-regulated disulphide may form within CD27 antigen between cysteines 117 and 120. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
56
PDB code
7kx0
Structure name
crystal structure of the cd27:cd70 co-stimulatory complex
Structure deposition date
2020-12-02
Thiol separation (Å)
7
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
117
Residue number B
120
Peptide name
CD27 antigen
Ligandability
Cysteine 117 of CD27 antigen
Cysteine 120 of CD27 antigen
5tlj X 64 X 84
A redox-regulated disulphide may form within CD27 antigen between cysteines 84 and 104 (64 and 84 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
5tlj
Structure name
complex between human cd27 and fab fragments of antibodies m2177 and m2191
Structure deposition date
2016-10-11
Thiol separation (Å)
8
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
84
Residue number B
104
Peptide name
CD27 antigen
Ligandability
Cysteine 84 of CD27 antigen
Cysteine 104 of CD27 antigen
5tl5 A 45 A 64
A redox-regulated disulphide may form within CD27 antigen between cysteines 65 and 84 (45 and 64 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
5tl5
Structure name
complex between human cd27 and antibody m2177
Structure deposition date
2016-10-10
Thiol separation (Å)
8
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
65
Residue number B
84
Peptide name
CD27 antigen
Ligandability
Cysteine 65 of CD27 antigen
Cysteine 84 of CD27 antigen
5tlj X 64 X 67
A redox-regulated disulphide may form within CD27 antigen between cysteines 84 and 87 (64 and 67 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
5tlj
Structure name
complex between human cd27 and fab fragments of antibodies m2177 and m2191
Structure deposition date
2016-10-11
Thiol separation (Å)
9
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
84
Residue number B
87
Peptide name
CD27 antigen
Ligandability
Cysteine 84 of CD27 antigen
Cysteine 87 of CD27 antigen
5tl5 A 84 A 97
A redox-regulated disulphide may form within CD27 antigen between cysteines 104 and 117 (84 and 97 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
5tl5
Structure name
complex between human cd27 and antibody m2177
Structure deposition date
2016-10-10
Thiol separation (Å)
8
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
104
Residue number B
117
Peptide name
CD27 antigen
Ligandability
Cysteine 104 of CD27 antigen
Cysteine 117 of CD27 antigen
8ds5 A 104 A 112
A redox-regulated disulphide may form within CD27 antigen between cysteines 104 and 112. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
51
PDB code
8ds5
Structure name
x-ray structure of the mk5890 fab - cd27 antibody-antigen complex
Structure deposition date
2022-07-21
Thiol separation (Å)
9
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
104
Residue number B
112
Peptide name
CD27 antigen
Ligandability
Cysteine 104 of CD27 antigen
Cysteine 112 of CD27 antigen
5tl5 A 7 A 20
A redox-regulated disulphide may form within CD27 antigen between cysteines 27 and 40 (7 and 20 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
5tl5
Structure name
complex between human cd27 and antibody m2177
Structure deposition date
2016-10-10
Thiol separation (Å)
8
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
27
Residue number B
40
Peptide name
CD27 antigen
Ligandability
Cysteine 27 of CD27 antigen
Cysteine 40 of CD27 antigen
7kx0 D 65 D 96
A redox-regulated disulphide may form within CD27 antigen between cysteines 65 and 96. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
7kx0
Structure name
crystal structure of the cd27:cd70 co-stimulatory complex
Structure deposition date
2020-12-02
Thiol separation (Å)
9
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
65
Residue number B
96
Peptide name
CD27 antigen
Ligandability
Cysteine 65 of CD27 antigen
Cysteine 96 of CD27 antigen
7kx0 E 104 E 120
A redox-regulated disulphide may form within CD27 antigen between cysteines 104 and 120. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
7kx0
Structure name
crystal structure of the cd27:cd70 co-stimulatory complex
Structure deposition date
2020-12-02
Thiol separation (Å)
8
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
104
Residue number B
120
Peptide name
CD27 antigen
Ligandability
Cysteine 104 of CD27 antigen
Cysteine 120 of CD27 antigen
5tl5 A 61 A 64
A redox-regulated disulphide may form within CD27 antigen between cysteines 81 and 84 (61 and 64 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
5tl5
Structure name
complex between human cd27 and antibody m2177
Structure deposition date
2016-10-10
Thiol separation (Å)
9
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
81
Residue number B
84
Peptide name
CD27 antigen
Ligandability
Cysteine 81 of CD27 antigen
Cysteine 84 of CD27 antigen
8ds5 A 43 A 81
A redox-regulated disulphide may form within CD27 antigen between cysteines 43 and 81. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
8ds5
Structure name
x-ray structure of the mk5890 fab - cd27 antibody-antigen complex
Structure deposition date
2022-07-21
Thiol separation (Å)
9
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
43
Residue number B
81
Peptide name
CD27 antigen
Ligandability
Cysteine 43 of CD27 antigen
Cysteine 81 of CD27 antigen
5tl5 A 84 A 86
A redox-regulated disulphide may form within CD27 antigen between cysteines 104 and 106 (84 and 86 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
5tl5
Structure name
complex between human cd27 and antibody m2177
Structure deposition date
2016-10-10
Thiol separation (Å)
9
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
104
Residue number B
106
Peptide name
CD27 antigen
Ligandability
Cysteine 104 of CD27 antigen
Cysteine 106 of CD27 antigen
7kx0 F 87 F 117
A redox-regulated disulphide may form within CD27 antigen between cysteines 87 and 117. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
7kx0
Structure name
crystal structure of the cd27:cd70 co-stimulatory complex
Structure deposition date
2020-12-02
Thiol separation (Å)
8
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
87
Residue number B
117
Peptide name
CD27 antigen
Ligandability
Cysteine 87 of CD27 antigen
Cysteine 117 of CD27 antigen
8ds5 A 43 A 65
A redox-regulated disulphide may form within CD27 antigen between cysteines 43 and 65. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
8ds5
Structure name
x-ray structure of the mk5890 fab - cd27 antibody-antigen complex
Structure deposition date
2022-07-21
Thiol separation (Å)
9
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
43
Residue number B
65
Peptide name
CD27 antigen
Ligandability
Cysteine 43 of CD27 antigen
Cysteine 65 of CD27 antigen
5tlk X 76 X 84
A redox-regulated disulphide may form within CD27 antigen between cysteines 96 and 104 (76 and 84 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
5tlk
Structure name
complex between human cd27 and fab fragments of antibodies m2177 and h2191
Structure deposition date
2016-10-11
Thiol separation (Å)
10
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
96
Residue number B
104
Peptide name
CD27 antigen
Ligandability
Cysteine 96 of CD27 antigen
Cysteine 104 of CD27 antigen
5tlj X 19 X 20
A redox-regulated disulphide may form within CD27 antigen between cysteines 39 and 40 (19 and 20 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
5tlj
Structure name
complex between human cd27 and fab fragments of antibodies m2177 and m2191
Structure deposition date
2016-10-11
Thiol separation (Å)
8
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
39
Residue number B
40
Peptide name
CD27 antigen
Ligandability
Cysteine 39 of CD27 antigen
Cysteine 40 of CD27 antigen
5tl5 A 7 A 33
A redox-regulated disulphide may form within CD27 antigen between cysteines 27 and 53 (7 and 33 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
5tl5
Structure name
complex between human cd27 and antibody m2177
Structure deposition date
2016-10-10
Thiol separation (Å)
9
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
27
Residue number B
53
Peptide name
CD27 antigen
Ligandability
Cysteine 27 of CD27 antigen
Cysteine 53 of CD27 antigen
7kx0 F 87 F 106
A redox-regulated disulphide may form within CD27 antigen between cysteines 87 and 106. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
7kx0
Structure name
crystal structure of the cd27:cd70 co-stimulatory complex
Structure deposition date
2020-12-02
Thiol separation (Å)
9
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
87
Residue number B
106
Peptide name
CD27 antigen
Ligandability
Cysteine 87 of CD27 antigen
Cysteine 106 of CD27 antigen
7kx0 F 87 F 120
A redox-regulated disulphide may form within CD27 antigen between cysteines 87 and 120. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
7kx0
Structure name
crystal structure of the cd27:cd70 co-stimulatory complex
Structure deposition date
2020-12-02
Thiol separation (Å)
9
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
87
Residue number B
120
Peptide name
CD27 antigen
Ligandability
Cysteine 87 of CD27 antigen
Cysteine 120 of CD27 antigen
5tlj X 33 X 42
A redox-regulated disulphide may form within CD27 antigen between cysteines 53 and 62 (33 and 42 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
5tlj
Structure name
complex between human cd27 and fab fragments of antibodies m2177 and m2191
Structure deposition date
2016-10-11
Thiol separation (Å)
9
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
53
Residue number B
62
Peptide name
CD27 antigen
Ligandability
Cysteine 53 of CD27 antigen
Cysteine 62 of CD27 antigen
5tlj X 19 X 33
A redox-regulated disulphide may form within CD27 antigen between cysteines 39 and 53 (19 and 33 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
5tlj
Structure name
complex between human cd27 and fab fragments of antibodies m2177 and m2191
Structure deposition date
2016-10-11
Thiol separation (Å)
9
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
39
Residue number B
53
Peptide name
CD27 antigen
Ligandability
Cysteine 39 of CD27 antigen
Cysteine 53 of CD27 antigen
8ds5 A 62 A 65
A redox-regulated disulphide may form within CD27 antigen between cysteines 62 and 65. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
8ds5
Structure name
x-ray structure of the mk5890 fab - cd27 antibody-antigen complex
Structure deposition date
2022-07-21
Thiol separation (Å)
10
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
62
Residue number B
65
Peptide name
CD27 antigen
Ligandability
Cysteine 62 of CD27 antigen
Cysteine 65 of CD27 antigen
7kx0 E 87 E 112
A redox-regulated disulphide may form within CD27 antigen between cysteines 87 and 112. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
7kx0
Structure name
crystal structure of the cd27:cd70 co-stimulatory complex
Structure deposition date
2020-12-02
Thiol separation (Å)
9
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
87
Residue number B
112
Peptide name
CD27 antigen
Ligandability
Cysteine 87 of CD27 antigen
Cysteine 112 of CD27 antigen
5tl5 A 42 A 61
A redox-regulated disulphide may form within CD27 antigen between cysteines 62 and 81 (42 and 61 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
5tl5
Structure name
complex between human cd27 and antibody m2177
Structure deposition date
2016-10-10
Thiol separation (Å)
10
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
62
Residue number B
81
Peptide name
CD27 antigen
Ligandability
Cysteine 62 of CD27 antigen
Cysteine 81 of CD27 antigen
5tlk X 20 X 42
A redox-regulated disulphide may form within CD27 antigen between cysteines 40 and 62 (20 and 42 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
5tlk
Structure name
complex between human cd27 and fab fragments of antibodies m2177 and h2191
Structure deposition date
2016-10-11
Thiol separation (Å)
9
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
40
Residue number B
62
Peptide name
CD27 antigen
Ligandability
Cysteine 40 of CD27 antigen
Cysteine 62 of CD27 antigen
7kx0 F 87 F 96
A redox-regulated disulphide may form within CD27 antigen between cysteines 87 and 96. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
7kx0
Structure name
crystal structure of the cd27:cd70 co-stimulatory complex
Structure deposition date
2020-12-02
Thiol separation (Å)
10
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
87
Residue number B
96
Peptide name
CD27 antigen
Ligandability
Cysteine 87 of CD27 antigen
Cysteine 96 of CD27 antigen
5tlk Y 61 Y 76
A redox-regulated disulphide may form within CD27 antigen between cysteines 81 and 96 (61 and 76 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
5tlk
Structure name
complex between human cd27 and fab fragments of antibodies m2177 and h2191
Structure deposition date
2016-10-11
Thiol separation (Å)
10
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
81
Residue number B
96
Peptide name
CD27 antigen
Ligandability
Cysteine 81 of CD27 antigen
Cysteine 96 of CD27 antigen
5tlj X 20 X 23
A redox-regulated disulphide may form within CD27 antigen between cysteines 40 and 43 (20 and 23 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
5tlj
Structure name
complex between human cd27 and fab fragments of antibodies m2177 and m2191
Structure deposition date
2016-10-11
Thiol separation (Å)
10
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26842
Residue number A
40
Residue number B
43
Peptide name
CD27 antigen
Ligandability
Cysteine 40 of CD27 antigen
Cysteine 43 of CD27 antigen
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