Interleukin-3 receptor subunit alpha
Intramolecular
Cysteine 217 and cysteine 293
Cysteine 151 and cysteine 165
Cysteine 112 and cysteine 122
Cysteine 52 and cysteine 68
Cysteine 76 and cysteine 195
Cysteine 122 and cysteine 151
Cysteine 122 and cysteine 165
Cysteine 112 and cysteine 165
Cysteine 112 and cysteine 151
5uwc G 217 G 293
A redox-regulated disulphide may form within Interleukin-3 receptor subunit alpha between cysteines 217 and 293.
Details
Redox score ?
87
PDB code
5uwc
Structure name
cytokine-receptor complex
Structure deposition date
2017-02-21
Thiol separation (Å)
3
Half-sphere exposure sum ?
nan
Minimum pKa ?
9
% buried
10
Peptide accession
P26951
Residue number A
217
Residue number B
293
Peptide name
Interleukin-3 receptor subunit alpha
Ligandability
Cysteine 217 of Interleukin-3 receptor subunit alpha
Cysteine 293 of Interleukin-3 receptor subunit alpha
6nmy M 151 M 165
A redox-regulated disulphide may form within Interleukin-3 receptor subunit alpha between cysteines 151 and 165.
Details
Redox score ?
86
PDB code
6nmy
Structure name
a cytokine-receptor complex
Structure deposition date
2019-01-13
Thiol separation (Å)
2
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26951
Residue number A
151
Residue number B
165
Peptide name
Interleukin-3 receptor subunit alpha
Ligandability
Cysteine 151 of Interleukin-3 receptor subunit alpha
Cysteine 165 of Interleukin-3 receptor subunit alpha
6nmy M 112 M 122
A redox-regulated disulphide may form within Interleukin-3 receptor subunit alpha between cysteines 112 and 122.
Details
Redox score ?
84
PDB code
6nmy
Structure name
a cytokine-receptor complex
Structure deposition date
2019-01-13
Thiol separation (Å)
2
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26951
Residue number A
112
Residue number B
122
Peptide name
Interleukin-3 receptor subunit alpha
Ligandability
Cysteine 112 of Interleukin-3 receptor subunit alpha
Cysteine 122 of Interleukin-3 receptor subunit alpha
6nmy F 52 F 68
A redox-regulated disulphide may form within Interleukin-3 receptor subunit alpha between cysteines 52 and 68.
Details
Redox score ?
82
PDB code
6nmy
Structure name
a cytokine-receptor complex
Structure deposition date
2019-01-13
Thiol separation (Å)
2
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26951
Residue number A
52
Residue number B
68
Peptide name
Interleukin-3 receptor subunit alpha
Ligandability
Cysteine 52 of Interleukin-3 receptor subunit alpha
Cysteine 68 of Interleukin-3 receptor subunit alpha
6nmy F 76 F 195
A redox-regulated disulphide may form within Interleukin-3 receptor subunit alpha between cysteines 76 and 195.
Details
Redox score ?
80
PDB code
6nmy
Structure name
a cytokine-receptor complex
Structure deposition date
2019-01-13
Thiol separation (Å)
2
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26951
Residue number A
76
Residue number B
195
Peptide name
Interleukin-3 receptor subunit alpha
Ligandability
Cysteine 76 of Interleukin-3 receptor subunit alpha
Cysteine 195 of Interleukin-3 receptor subunit alpha
5uv8 G 122 G 151
A redox-regulated disulphide may form within Interleukin-3 receptor subunit alpha between cysteines 122 and 151.
Details
Redox score ?
60
PDB code
5uv8
Structure name
interleukin-3 receptor complex
Structure deposition date
2017-02-19
Thiol separation (Å)
7
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26951
Residue number A
122
Residue number B
151
Peptide name
Interleukin-3 receptor subunit alpha
Ligandability
Cysteine 122 of Interleukin-3 receptor subunit alpha
Cysteine 151 of Interleukin-3 receptor subunit alpha
6nmy M 122 M 165
A redox-regulated disulphide may form within Interleukin-3 receptor subunit alpha between cysteines 122 and 165. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
58
PDB code
6nmy
Structure name
a cytokine-receptor complex
Structure deposition date
2019-01-13
Thiol separation (Å)
6
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26951
Residue number A
122
Residue number B
165
Peptide name
Interleukin-3 receptor subunit alpha
Ligandability
Cysteine 122 of Interleukin-3 receptor subunit alpha
Cysteine 165 of Interleukin-3 receptor subunit alpha
6nmy F 112 F 165
A redox-regulated disulphide may form within Interleukin-3 receptor subunit alpha between cysteines 112 and 165. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
51
PDB code
6nmy
Structure name
a cytokine-receptor complex
Structure deposition date
2019-01-13
Thiol separation (Å)
8
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
P26951
Residue number A
112
Residue number B
165
Peptide name
Interleukin-3 receptor subunit alpha
Ligandability
Cysteine 112 of Interleukin-3 receptor subunit alpha
Cysteine 165 of Interleukin-3 receptor subunit alpha
5uwc G 112 G 151
A redox-regulated disulphide may form within Interleukin-3 receptor subunit alpha between cysteines 112 and 151. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
5uwc
Structure name
cytokine-receptor complex
Structure deposition date
2017-02-21
Thiol separation (Å)
10
Half-sphere exposure sum ?
64
Minimum pKa ?
9
% buried
nan
Peptide accession
P26951
Residue number A
112
Residue number B
151
Peptide name
Interleukin-3 receptor subunit alpha
Ligandability
Cysteine 112 of Interleukin-3 receptor subunit alpha
Cysteine 151 of Interleukin-3 receptor subunit alpha
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