Gamma-aminobutyric acid receptor subunit beta-3

Intramolecular

A redox-regulated disulphide may form within Gamma-aminobutyric acid receptor subunit beta-3 between cysteines 161 and 175 (136 and 150 respectively in this structure).

Details

Redox score ?

PDB code

7qne

Structure name

cryo-em structure of human full-length synaptic alpha1beta3gamma2 gaba(a)r in complex with ro15-4513 and megabody mb38

Structure deposition date

2021-12-20

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

P28472

Residue number A

161

Residue number B

175

Peptide name

Gamma-aminobutyric acid receptor subunit beta-3

Ligandability

Cysteine 161 of Gamma-aminobutyric acid receptor subunit beta-3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.