Retinoic acid receptor RXR-beta

Intramolecular

A redox-regulated disulphide may form within Retinoic acid receptor RXR-beta between cysteines 340 and 503. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

1h9u

Structure name

the structure of the human retinoid-x-receptor beta ligand binding domain in complex with the specific synthetic agonist lg100268

Structure deposition date

2001-03-21

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

P28702

Residue number A

340

Residue number B

503

Peptide name

Retinoic acid receptor RXR-beta

Ligandability

Cysteine 340 of Retinoic acid receptor RXR-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 503 of Retinoic acid receptor RXR-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Retinoic acid receptor RXR-beta between cysteines 440 and 475. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?