Cytidine deaminase
Intermolecular
Cysteine 59 and cysteine 65
Cysteine 59 and cysteine 99
Cysteine 59 and cysteine 102
Cysteine 99 and cysteine 99
Intramolecular
Cysteine 65 and cysteine 102
Cysteine 65 and cysteine 99
Cysteine 99 and cysteine 102
Cysteine 31 and cysteine 53
1mq0 A 59 B 65
A redox-regulated disulphide may form between two units of Cytidine deaminase at cysteines 59 and 65.
Details
Redox score ?
78
PDB code
1mq0
Structure name
crystal structure of human cytidine deaminase
Structure deposition date
2002-09-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
74
Minimum pKa ?
5
% buried
76
Peptide A name
Cytidine deaminase
Peptide B name
Cytidine deaminase
Peptide A accession
P32320
Peptide B accession
P32320
Peptide A residue number
59
Peptide B residue number
65
Ligandability
Cysteine 59 of Cytidine deaminase
Cysteine 65 of Cytidine deaminase
1mq0 A 59 B 99
A redox-regulated disulphide may form between two units of Cytidine deaminase at cysteines 59 and 99. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
56
PDB code
1mq0
Structure name
crystal structure of human cytidine deaminase
Structure deposition date
2002-09-13
Thiol separation (Å)
3
Half-sphere exposure sum ?
54
Minimum pKa ?
19
% buried
nan
Peptide A name
Cytidine deaminase
Peptide B name
Cytidine deaminase
Peptide A accession
P32320
Peptide B accession
P32320
Peptide A residue number
59
Peptide B residue number
99
Ligandability
Cysteine 59 of Cytidine deaminase
Cysteine 99 of Cytidine deaminase
1mq0 A 59 B 102
A redox-regulated disulphide may form between two units of Cytidine deaminase at cysteines 59 and 102. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
1mq0
Structure name
crystal structure of human cytidine deaminase
Structure deposition date
2002-09-13
Thiol separation (Å)
6
Half-sphere exposure sum ?
61
Minimum pKa ?
19
% buried
80
Peptide A name
Cytidine deaminase
Peptide B name
Cytidine deaminase
Peptide A accession
P32320
Peptide B accession
P32320
Peptide A residue number
59
Peptide B residue number
102
Ligandability
Cysteine 59 of Cytidine deaminase
Cysteine 102 of Cytidine deaminase
2fr6 C 99 D 99
A redox-regulated disulphide may form between two units of Cytidine deaminase at cysteines 99 and 99. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
31
PDB code
2fr6
Structure name
crystal structure of mouse cytidine deaminase complexed with cytidine
Structure deposition date
2006-01-19
Thiol separation (Å)
10
Half-sphere exposure sum ?
88
Minimum pKa ?
nan
% buried
nan
Peptide A name
Cytidine deaminase
Peptide B name
Cytidine deaminase
Peptide A accession
P56389
Peptide B accession
P56389
Peptide A residue number
99
Peptide B residue number
99
Ligandability
1mq0 B 65 B 102
A redox-regulated disulphide may form within Cytidine deaminase between cysteines 65 and 102.
Details
Redox score ?
78
PDB code
1mq0
Structure name
crystal structure of human cytidine deaminase
Structure deposition date
2002-09-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
75
Minimum pKa ?
5
% buried
86
Peptide accession
P32320
Residue number A
65
Residue number B
102
Peptide name
Cytidine deaminase
Ligandability
Cysteine 65 of Cytidine deaminase
Cysteine 102 of Cytidine deaminase
1mq0 A 65 A 99
A redox-regulated disulphide may form within Cytidine deaminase between cysteines 65 and 99.
Details
Redox score ?
74
PDB code
1mq0
Structure name
crystal structure of human cytidine deaminase
Structure deposition date
2002-09-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
72
Minimum pKa ?
7
% buried
nan
Peptide accession
P32320
Residue number A
65
Residue number B
99
Peptide name
Cytidine deaminase
Ligandability
Cysteine 65 of Cytidine deaminase
Cysteine 99 of Cytidine deaminase
1mq0 A 99 A 102
A redox-regulated disulphide may form within Cytidine deaminase between cysteines 99 and 102. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
1mq0
Structure name
crystal structure of human cytidine deaminase
Structure deposition date
2002-09-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
21
% buried
nan
Peptide accession
P32320
Residue number A
99
Residue number B
102
Peptide name
Cytidine deaminase
Ligandability
Cysteine 99 of Cytidine deaminase
Cysteine 102 of Cytidine deaminase
2fr6 B 31 B 53
A redox-regulated disulphide may form within Cytidine deaminase between cysteines 31 and 53. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
2fr6
Structure name
crystal structure of mouse cytidine deaminase complexed with cytidine
Structure deposition date
2006-01-19
Thiol separation (Å)
8
Half-sphere exposure sum ?
76
Minimum pKa ?
12
% buried
78
Peptide accession
P56389
Residue number A
31
Residue number B
53
Peptide name
Cytidine deaminase
Ligandability
Cysteine 31 of Cytidine deaminase
Cysteine 53 of Cytidine deaminase
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