ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

CD70 antigen

Intramolecular
Cysteine 115 and cysteine 151
Cysteine 133 and cysteine 168
A redox-regulated disulphide may form within CD70 antigen between cysteines 115 and 151.

Details

Redox score ?
80
PDB code
7kx0
Structure name
crystal structure of the cd27:cd70 co-stimulatory complex
Structure deposition date
2020-12-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
P32970
Residue number A
115
Residue number B
151
Peptide name
CD70 antigen

Ligandability

Cysteine 115 of CD70 antigen

Cysteine 151 of CD70 antigen

A redox-regulated disulphide may form within CD70 antigen between cysteines 133 and 168.

Details

Redox score ?
80
PDB code
7kx0
Structure name
crystal structure of the cd27:cd70 co-stimulatory complex
Structure deposition date
2020-12-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
P32970
Residue number A
133
Residue number B
168
Peptide name
CD70 antigen

Ligandability

Cysteine 133 of CD70 antigen

Cysteine 168 of CD70 antigen

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