ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

Intramolecular
Cysteine 166 and cysteine 222 L
A redox-regulated disulphide may form within Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial between cysteines 166 and 222 (78 and 134 respectively in this structure).

Details

Redox score ?
65
PDB code
2hqu
Structure name
human dutpase in complex with alpha,beta-iminodutp and magnesium ion
Structure deposition date
2006-07-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
82
Minimum pKa ?
8
% buried
92
Peptide accession
P33316
Residue number A
166
Residue number B
222
Peptide name
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

Ligandability

Cysteine 166 of Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

Cysteine 222 of Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

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