ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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ATP-binding cassette sub-family D member 1

Intermolecular
Cysteine 511 and cysteine 717
A redox-regulated disulphide may form between two units of ATP-binding cassette sub-family D member 1 at cysteines 511 and 717. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
41
PDB code
7vwc
Structure name
cryo-em structure of human very long-chain fatty acid abc transporter abcd1
Structure deposition date
2021-11-10
Thiol separation (Å)
10
Half-sphere exposure sum ?
51
Minimum pKa ?
10
% buried
44
Peptide A name
ATP-binding cassette sub-family D member 1
Peptide B name
ATP-binding cassette sub-family D member 1
Peptide A accession
P33897
Peptide B accession
P33897
Peptide A residue number
511
Peptide B residue number
717

Ligandability

Cysteine 511 of ATP-binding cassette sub-family D member 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 717 of ATP-binding cassette sub-family D member 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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