ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

Intramolecular
Cysteine 478 and cysteine 510
A redox-regulated disulphide may form within Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA between cysteines 478 and 510.

Details

Redox score ?
78
PDB code
5kkb
Structure name
structure of mouse golgi alpha-1,2-mannosidase ia and man9glcnac2-pa complex
Structure deposition date
2016-06-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
99
Minimum pKa ?
nan
% buried
nan
Peptide accession
P45700
Residue number A
478
Residue number B
510
Peptide name
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

Ligandability

Cysteine 478 of Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 510 of Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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