Ribonuclease 4
Intramolecular
Cysteine 67 and cysteine 120
Cysteine 92 and cysteine 99
Cysteine 53 and cysteine 109
Cysteine 85 and cysteine 135
Cysteine 99 and cysteine 135
Cysteine 92 and cysteine 135
Cysteine 85 and cysteine 99
2rnf A 39 A 92
A redox-regulated disulphide may form within Ribonuclease 4 between cysteines 67 and 120 (39 and 92 respectively in this structure).
Details
Redox score ?
87
PDB code
2rnf
Structure name
x-ray crystal structure of human ribonuclease 4 in complex with d(up)
Structure deposition date
1998-11-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P34096
Residue number A
67
Residue number B
120
Peptide name
Ribonuclease 4
Ligandability
Cysteine 67 of Ribonuclease 4
Cysteine 120 of Ribonuclease 4
1rnf B 64 B 71
A redox-regulated disulphide may form within Ribonuclease 4 between cysteines 92 and 99 (64 and 71 respectively in this structure).
Details
Redox score ?
86
PDB code
1rnf
Structure name
x-ray crystal structure of unliganded human ribonuclease 4
Structure deposition date
1998-10-29
Thiol separation (Å)
2
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
P34096
Residue number A
92
Residue number B
99
Peptide name
Ribonuclease 4
Ligandability
Cysteine 92 of Ribonuclease 4
Cysteine 99 of Ribonuclease 4
2rnf B 25 B 81
A redox-regulated disulphide may form within Ribonuclease 4 between cysteines 53 and 109 (25 and 81 respectively in this structure).
Details
Redox score ?
86
PDB code
2rnf
Structure name
x-ray crystal structure of human ribonuclease 4 in complex with d(up)
Structure deposition date
1998-11-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
P34096
Residue number A
53
Residue number B
109
Peptide name
Ribonuclease 4
Ligandability
Cysteine 53 of Ribonuclease 4
Cysteine 109 of Ribonuclease 4
2rnf A 57 A 107
A redox-regulated disulphide may form within Ribonuclease 4 between cysteines 85 and 135 (57 and 107 respectively in this structure).
Details
Redox score ?
83
PDB code
2rnf
Structure name
x-ray crystal structure of human ribonuclease 4 in complex with d(up)
Structure deposition date
1998-11-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
P34096
Residue number A
85
Residue number B
135
Peptide name
Ribonuclease 4
Ligandability
Cysteine 85 of Ribonuclease 4
Cysteine 135 of Ribonuclease 4
2rnf B 71 B 107
A redox-regulated disulphide may form within Ribonuclease 4 between cysteines 99 and 135 (71 and 107 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
2rnf
Structure name
x-ray crystal structure of human ribonuclease 4 in complex with d(up)
Structure deposition date
1998-11-03
Thiol separation (Å)
8
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
P34096
Residue number A
99
Residue number B
135
Peptide name
Ribonuclease 4
Ligandability
Cysteine 99 of Ribonuclease 4
Cysteine 135 of Ribonuclease 4
1rnf B 64 B 107
A redox-regulated disulphide may form within Ribonuclease 4 between cysteines 92 and 135 (64 and 107 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
1rnf
Structure name
x-ray crystal structure of unliganded human ribonuclease 4
Structure deposition date
1998-10-29
Thiol separation (Å)
9
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P34096
Residue number A
92
Residue number B
135
Peptide name
Ribonuclease 4
Ligandability
Cysteine 92 of Ribonuclease 4
Cysteine 135 of Ribonuclease 4
1rnf A 57 A 71
A redox-regulated disulphide may form within Ribonuclease 4 between cysteines 85 and 99 (57 and 71 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
1rnf
Structure name
x-ray crystal structure of unliganded human ribonuclease 4
Structure deposition date
1998-10-29
Thiol separation (Å)
10
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
P34096
Residue number A
85
Residue number B
99
Peptide name
Ribonuclease 4
Ligandability
Cysteine 85 of Ribonuclease 4
Cysteine 99 of Ribonuclease 4
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