ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Phosphoglucomutase-1

Intramolecular
Cysteine 238 and cysteine 251
A redox-regulated disulphide may form within Phosphoglucomutase-1 between cysteines 238 and 251 (237 and 250 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
53
PDB code
3pmg
Structure name
structure of rabbit muscle phosphoglucomutase at 2
Structure deposition date
1995-03-02
Thiol separation (Å)
7
Half-sphere exposure sum ?
62
Minimum pKa ?
11
% buried
62
Peptide accession
P00949
Residue number A
238
Residue number B
251
Peptide name
Phosphoglucomutase-1

Ligandability

Cysteine 238 of Phosphoglucomutase-1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 251 of Phosphoglucomutase-1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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