ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Tumor necrosis factor receptor superfamily member 3

Intramolecular
Cysteine 126 and cysteine 59
Cysteine 58 and cysteine 142
Cysteine 191 and cysteine 210 L
Cysteine 170 and cysteine 185
Cysteine 43 and cysteine 58
Cysteine 104 and cysteine 124
Cysteine 148 and cysteine 167
Cysteine 83 and cysteine 98
Cysteine 62 and cysteine 80
Cysteine 101 and cysteine 116
More...
Cysteine 59 and cysteine 72
Cysteine 126 and cysteine 142
Cysteine 126 and cysteine 58
Cysteine 59 and cysteine 142
Cysteine 58 and cysteine 59
Cysteine 124 and cysteine 59
Cysteine 124 and cysteine 126
Cysteine 43 and cysteine 59
Cysteine 148 and cysteine 185
Cysteine 83 and cysteine 101
Cysteine 104 and cysteine 126
Cysteine 104 and cysteine 59
Cysteine 58 and cysteine 72
Cysteine 62 and cysteine 83
Cysteine 167 and cysteine 185
Cysteine 43 and cysteine 72
Cysteine 80 and cysteine 83
Cysteine 62 and cysteine 72
Cysteine 72 and cysteine 80
Cysteine 148 and cysteine 170
Cysteine 116 and cysteine 124
Cysteine 104 and cysteine 116
Cysteine 59 and cysteine 62
Cysteine 98 and cysteine 101
Cysteine 62 and cysteine 98
Cysteine 59 and cysteine 80
A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 126 and 59 (126 and 139 respectively in this structure).

Details

Redox score ?
94
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
126
Residue number B
59
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 126 of Tumor necrosis factor receptor superfamily member 3

Cysteine 59 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 58 and 142 (132 and 142 respectively in this structure).

Details

Redox score ?
91
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
58
Residue number B
142
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 58 of Tumor necrosis factor receptor superfamily member 3

Cysteine 142 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 191 and 210.

Details

Redox score ?
90
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
40
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
191
Residue number B
210
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 191 of Tumor necrosis factor receptor superfamily member 3

Cysteine 210 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 170 and 185.

Details

Redox score ?
89
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
170
Residue number B
185
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 170 of Tumor necrosis factor receptor superfamily member 3

Cysteine 185 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 43 and 58.

Details

Redox score ?
89
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
43
Residue number B
58
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 43 of Tumor necrosis factor receptor superfamily member 3

Cysteine 58 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 104 and 124.

Details

Redox score ?
89
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
38
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
104
Residue number B
124
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 104 of Tumor necrosis factor receptor superfamily member 3

Cysteine 124 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 148 and 167.

Details

Redox score ?
88
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
148
Residue number B
167
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 148 of Tumor necrosis factor receptor superfamily member 3

Cysteine 167 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 83 and 98.

Details

Redox score ?
88
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
83
Residue number B
98
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 83 of Tumor necrosis factor receptor superfamily member 3

Cysteine 98 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 62 and 80.

Details

Redox score ?
87
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
62
Residue number B
80
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 62 of Tumor necrosis factor receptor superfamily member 3

Cysteine 80 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 101 and 116.

Details

Redox score ?
86
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
101
Residue number B
116
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 101 of Tumor necrosis factor receptor superfamily member 3

Cysteine 116 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 59 and 72.

Details

Redox score ?
86
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
59
Residue number B
72
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 59 of Tumor necrosis factor receptor superfamily member 3

Cysteine 72 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 126 and 142.

Details

Redox score ?
74
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
5
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
126
Residue number B
142
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 126 of Tumor necrosis factor receptor superfamily member 3

Cysteine 142 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 126 and 58 (126 and 132 respectively in this structure).

Details

Redox score ?
70
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
6
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
126
Residue number B
58
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 126 of Tumor necrosis factor receptor superfamily member 3

Cysteine 58 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 59 and 142 (139 and 142 respectively in this structure).

Details

Redox score ?
68
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
6
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
59
Residue number B
142
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 59 of Tumor necrosis factor receptor superfamily member 3

Cysteine 142 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 58 and 59 (132 and 139 respectively in this structure).

Details

Redox score ?
65
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
7
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
58
Residue number B
59
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 58 of Tumor necrosis factor receptor superfamily member 3

Cysteine 59 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 124 and 59 (124 and 139 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
54
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
9
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
124
Residue number B
59
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 124 of Tumor necrosis factor receptor superfamily member 3

Cysteine 59 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 124 and 126. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
53
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
9
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
124
Residue number B
126
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 124 of Tumor necrosis factor receptor superfamily member 3

Cysteine 126 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 43 and 59. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
53
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
8
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
43
Residue number B
59
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 43 of Tumor necrosis factor receptor superfamily member 3

Cysteine 59 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 148 and 185. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
50
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
9
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
148
Residue number B
185
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 148 of Tumor necrosis factor receptor superfamily member 3

Cysteine 185 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 83 and 101. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
49
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
9
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
83
Residue number B
101
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 83 of Tumor necrosis factor receptor superfamily member 3

Cysteine 101 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 104 and 126. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
49
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
9
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
104
Residue number B
126
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 104 of Tumor necrosis factor receptor superfamily member 3

Cysteine 126 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 104 and 59 (104 and 139 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
48
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
9
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
104
Residue number B
59
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 104 of Tumor necrosis factor receptor superfamily member 3

Cysteine 59 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 58 and 72. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
48
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
9
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
58
Residue number B
72
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 58 of Tumor necrosis factor receptor superfamily member 3

Cysteine 72 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 62 and 83. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
47
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
9
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
62
Residue number B
83
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 62 of Tumor necrosis factor receptor superfamily member 3

Cysteine 83 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 167 and 185. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
46
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
9
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
167
Residue number B
185
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 167 of Tumor necrosis factor receptor superfamily member 3

Cysteine 185 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 43 and 72. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
46
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
10
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
43
Residue number B
72
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 43 of Tumor necrosis factor receptor superfamily member 3

Cysteine 72 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 80 and 83. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
46
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
10
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
80
Residue number B
83
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 80 of Tumor necrosis factor receptor superfamily member 3

Cysteine 83 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 62 and 72. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
45
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
9
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
62
Residue number B
72
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 62 of Tumor necrosis factor receptor superfamily member 3

Cysteine 72 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 72 and 80. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
45
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
10
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
72
Residue number B
80
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 72 of Tumor necrosis factor receptor superfamily member 3

Cysteine 80 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 148 and 170. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
45
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
10
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
148
Residue number B
170
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 148 of Tumor necrosis factor receptor superfamily member 3

Cysteine 170 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 116 and 124. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
44
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
10
Half-sphere exposure sum ?
46
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
116
Residue number B
124
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 116 of Tumor necrosis factor receptor superfamily member 3

Cysteine 124 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 104 and 116. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
44
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
10
Half-sphere exposure sum ?
47
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
104
Residue number B
116
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 104 of Tumor necrosis factor receptor superfamily member 3

Cysteine 116 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 59 and 62. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
43
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
9
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
59
Residue number B
62
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 59 of Tumor necrosis factor receptor superfamily member 3

Cysteine 62 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 98 and 101. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
41
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
9
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
98
Residue number B
101
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 98 of Tumor necrosis factor receptor superfamily member 3

Cysteine 101 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 62 and 98. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
40
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
10
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
62
Residue number B
98
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 62 of Tumor necrosis factor receptor superfamily member 3

Cysteine 98 of Tumor necrosis factor receptor superfamily member 3

A redox-regulated disulphide may form within Tumor necrosis factor receptor superfamily member 3 between cysteines 59 and 80. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
40
PDB code
4mxw
Structure name
structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab
Structure deposition date
2013-09-26
Thiol separation (Å)
10
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P36941
Residue number A
59
Residue number B
80
Peptide name
Tumor necrosis factor receptor superfamily member 3

Ligandability

Cysteine 59 of Tumor necrosis factor receptor superfamily member 3

Cysteine 80 of Tumor necrosis factor receptor superfamily member 3

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