Squalene synthase

Intramolecular

A redox-regulated disulphide may form within Squalene synthase between cysteines 43 and 70. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

3wei

Structure name

crystal structure of the human squalene synthase y73a mutant in complex with presqualene pyrophosphate

Structure deposition date

2013-07-07

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

P37268

Residue number A

Residue number B

Peptide name

Squalene synthase

Ligandability

Cysteine 43 of Squalene synthase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.