ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Macrophage-capping protein

Intramolecular
Cysteine 165 and cysteine 178
A redox-regulated disulphide may form within Macrophage-capping protein between cysteines 165 and 178 (164 and 177 respectively in this structure).

Details

Redox score ?
76
PDB code
1j72
Structure name
crystal structure of mutant macrophage capping protein (cap g) with actin-severing activity in the ca2+-free form
Structure deposition date
2001-05-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
82
Minimum pKa ?
7
% buried
58
Peptide accession
P40121
Residue number A
165
Residue number B
178
Peptide name
Macrophage-capping protein

Ligandability

Cysteine 165 of Macrophage-capping protein

Cysteine 178 of Macrophage-capping protein

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