ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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OX-2 membrane glycoprotein

Intramolecular
Cysteine 51 and cysteine 121
Cysteine 160 and cysteine 214
Cysteine 118 and cysteine 136
A redox-regulated disulphide may form within OX-2 membrane glycoprotein between cysteines 51 and 121 (21 and 91 respectively in this structure).

Details

Redox score ?
80
PDB code
4bfi
Structure name
structure of the complex of the extracellular portions of mouse cd200r and mouse cd200
Structure deposition date
2013-03-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
83
Minimum pKa ?
nan
% buried
nan
Peptide accession
O54901
Residue number A
51
Residue number B
121
Peptide name
OX-2 membrane glycoprotein

Ligandability

Cysteine 51 of OX-2 membrane glycoprotein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 121 of OX-2 membrane glycoprotein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within OX-2 membrane glycoprotein between cysteines 160 and 214 (130 and 184 respectively in this structure).

Details

Redox score ?
80
PDB code
4bfi
Structure name
structure of the complex of the extracellular portions of mouse cd200r and mouse cd200
Structure deposition date
2013-03-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
O54901
Residue number A
160
Residue number B
214
Peptide name
OX-2 membrane glycoprotein

Ligandability

Cysteine 160 of OX-2 membrane glycoprotein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 214 of OX-2 membrane glycoprotein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within OX-2 membrane glycoprotein between cysteines 118 and 136 (88 and 106 respectively in this structure).

Details

Redox score ?
80
PDB code
4bfi
Structure name
structure of the complex of the extracellular portions of mouse cd200r and mouse cd200
Structure deposition date
2013-03-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
O54901
Residue number A
118
Residue number B
136
Peptide name
OX-2 membrane glycoprotein

Ligandability

Cysteine 118 of OX-2 membrane glycoprotein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 136 of OX-2 membrane glycoprotein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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