ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Reduced folate transporter

Intramolecular
Cysteine 30 and cysteine 33
A redox-regulated disulphide may form within Reduced folate transporter between cysteines 30 and 33. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
54
PDB code
7xq2
Structure name
structure of hslc19a1+2'3'-cgamp
Structure deposition date
2022-05-06
Thiol separation (Å)
7
Half-sphere exposure sum ?
55
Minimum pKa ?
9
% buried
26
Peptide accession
P41440
Residue number A
30
Residue number B
33
Peptide name
Reduced folate transporter

Ligandability

Cysteine 30 of Reduced folate transporter

Cysteine 33 of Reduced folate transporter

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