Signal transducer and activator of transcription 5A

Intramolecular

A redox-regulated disulphide may form within Signal transducer and activator of transcription 5A between cysteines 400 and 401. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

7ubt

Structure name

stat5a core in complex with compound 18

Structure deposition date

2022-03-15

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

P42229

Residue number A

400

Residue number B

401

Peptide name

Signal transducer and activator of transcription 5A

Ligandability

Cysteine 400 of Signal transducer and activator of transcription 5A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.