Excitatory amino acid transporter 3
7nsg B 158 C 158
A redox-regulated disulphide may form between two units of Excitatory amino acid transporter 3 at cysteines 158 and 158. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
27
PDB code
7nsg
Structure name
structure of human excitatory amino acid transporter 3 (eaat3) in complex with hip-b
Structure deposition date
2021-03-05
Thiol separation (Å)
10
Half-sphere exposure sum ?
76
Minimum pKa ?
12
% buried
100
Peptide A name
Excitatory amino acid transporter 3
Peptide B name
Excitatory amino acid transporter 3
Peptide A accession
P43005
Peptide B accession
P43005
Peptide A residue number
158
Peptide B residue number
158
Ligandability
6x3e B 158 B 219
A redox-regulated disulphide may form within Excitatory amino acid transporter 3 between cysteines 158 and 219. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
33
PDB code
6x3e
Structure name
heaat3-asymmetric-1o2i
Structure deposition date
2020-05-21
Thiol separation (Å)
9
Half-sphere exposure sum ?
82
Minimum pKa ?
12
% buried
100
Peptide accession
P43005
Residue number A
158
Residue number B
219
Peptide name
Excitatory amino acid transporter 3
Ligandability
Cysteine 158 of Excitatory amino acid transporter 3
Cysteine 219 of Excitatory amino acid transporter 3
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