Killer cell immunoglobulin-like receptor 2DL2

Intramolecular

A redox-regulated disulphide may form within Killer cell immunoglobulin-like receptor 2DL2 between cysteines 149 and 198 (128 and 177 respectively in this structure).

Details

Redox score ?

PDB code

6pa1

Structure name

killer cell immunoglobulin-like receptor 2dl2 in complex with hla- c*07:02

Structure deposition date

2019-06-11

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide accession

P43627

Residue number A

149

Residue number B

198

Peptide name

Killer cell immunoglobulin-like receptor 2DL2

Ligandability

Cysteine 149 of Killer cell immunoglobulin-like receptor 2DL2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 198 of Killer cell immunoglobulin-like receptor 2DL2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Killer cell immunoglobulin-like receptor 2DL2 between cysteines 49 and 100 (28 and 79 respectively in this structure).

Details

Redox score ?

PDB code

6pa1

Structure name

killer cell immunoglobulin-like receptor 2dl2 in complex with hla- c*07:02

Structure deposition date

2019-06-11

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide accession

P43627

Residue number A

Residue number B

100

Peptide name

Killer cell immunoglobulin-like receptor 2DL2

Ligandability

Cysteine 49 of Killer cell immunoglobulin-like receptor 2DL2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 100 of Killer cell immunoglobulin-like receptor 2DL2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Killer cell immunoglobulin-like receptor 2DL2 between cysteines 149 and 169 (128 and 148 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?