ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Killer cell immunoglobulin-like receptor 2DS4

Intramolecular
Cysteine 149 and cysteine 198
Cysteine 49 and cysteine 100
A redox-regulated disulphide may form within Killer cell immunoglobulin-like receptor 2DS4 between cysteines 149 and 198 (128 and 177 respectively in this structure).

Details

Redox score ?
81
PDB code
3h8n
Structure name
crystal structure analysis of kir2ds4
Structure deposition date
2009-04-29
Thiol separation (Å)
2
Half-sphere exposure sum ?
89
Minimum pKa ?
nan
% buried
nan
Peptide accession
P43632
Residue number A
149
Residue number B
198
Peptide name
Killer cell immunoglobulin-like receptor 2DS4

Ligandability

Cysteine 149 of Killer cell immunoglobulin-like receptor 2DS4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 198 of Killer cell immunoglobulin-like receptor 2DS4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Killer cell immunoglobulin-like receptor 2DS4 between cysteines 49 and 100 (28 and 79 respectively in this structure).

Details

Redox score ?
80
PDB code
3h8n
Structure name
crystal structure analysis of kir2ds4
Structure deposition date
2009-04-29
Thiol separation (Å)
2
Half-sphere exposure sum ?
90
Minimum pKa ?
nan
% buried
nan
Peptide accession
P43632
Residue number A
49
Residue number B
100
Peptide name
Killer cell immunoglobulin-like receptor 2DS4

Ligandability

Cysteine 49 of Killer cell immunoglobulin-like receptor 2DS4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 100 of Killer cell immunoglobulin-like receptor 2DS4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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