a tool for identifying drug-targetable redox-active disulphides

Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial

Intramolecular

Cysteine 308 and cysteine 385

A redox-regulated disulphide may form within Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial between cysteines 308 and 385.

Details

Redox score ?

68

PDB code

Structure name

structure of human short-branched chain acyl-coa dehydrogenase (acadsb)

Structure deposition date

2007-02-28

Thiol separation (Å)

4

Half-sphere exposure sum ?

89

Minimum pK_a ?

9

% buried

100

Peptide accession

Residue number A

308

Residue number B

385

Peptide name

Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial

Ligandability

Cysteine 308 of Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 385 of Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: