ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Ran GTPase-activating protein 1

Intermolecular
Cysteine 138 of SUMO-conjugating enzyme UBC9 and cysteine 575 L
A redox-regulated disulphide may form between cysteine 138 of SUMO-conjugating enzyme UBC9 and cysteine 575 of Ran GTPase-activating protein 1.

Details

Redox score ?
82
PDB code
1kps
Structure name
structural basis for e2-mediated sumo conjugation revealed by a complex between ubiquitin conjugating enzyme ubc9 and rangap1
Structure deposition date
2002-01-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide A name
SUMO-conjugating enzyme UBC9
Peptide B name
Ran GTPase-activating protein 1
Peptide A accession
P63279
Peptide B accession
P46061
Peptide A residue number
138
Peptide B residue number
575

Ligandability

Cysteine 138 of SUMO-conjugating enzyme UBC9

Cysteine 575 of Ran GTPase-activating protein 1

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