ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Crk-like protein

Intermolecular
Cysteine 249 and cysteine 249 L
A redox-regulated disulphide may form between two units of Crk-like protein at cysteines 249 and 249 (13 and 13 respectively in this structure).

Details

Redox score ?
64
PDB code
2bzy
Structure name
homodimer of crkl-sh3c domain
Structure deposition date
2005-08-24
Thiol separation (Å)
6
Half-sphere exposure sum ?
37
Minimum pKa ?
9
% buried
0
Peptide A name
Crk-like protein
Peptide B name
Crk-like protein
Peptide A accession
P46109
Peptide B accession
P46109
Peptide A residue number
249
Peptide B residue number
249

Ligandability

If this tool was useful for finding a disulphide, please cite: