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Neurogenic locus notch homolog protein 1

Intramolecular
Cysteine 299 and cysteine 312
Cysteine 266 and cysteine 281
Cysteine 149 and cysteine 164
Cysteine 166 and cysteine 175
Cysteine 227 and cysteine 243
Cysteine 499 and cysteine 514
Cysteine 461 and cysteine 476
Cysteine 283 and cysteine 292
Cysteine 1449 and cysteine 1472
Cysteine 381 and cysteine 398
More...
Cysteine 516 and cysteine 525
Cysteine 189 and cysteine 204
Cysteine 245 and cysteine 254
Cysteine 1454 and cysteine 1467
Cysteine 206 and cysteine 215
Cysteine 339 and cysteine 350
Cysteine 987 and cysteine 998
Cysteine 478 and cysteine 487
Cysteine 494 and cysteine 505
Cysteine 416 and cysteine 429
Cysteine 456 and cysteine 467
Cysteine 423 and cysteine 438
Cysteine 182 and cysteine 195
Cysteine 144 and cysteine 155
Cysteine 306 and cysteine 321
Cysteine 344 and cysteine 359
Cysteine 440 and cysteine 449
Cysteine 222 and cysteine 233
Cysteine 261 and cysteine 272
Cysteine 400 and cysteine 409
Cysteine 361 and cysteine 370
Cysteine 1490 and cysteine 1514
Cysteine 376 and cysteine 387
Cysteine 1192 and cysteine 476
Cysteine 323 and cysteine 332
Cysteine 992 and cysteine 1007
Cysteine 1496 and cysteine 1509
Cysteine 456 and cysteine 1198
Cysteine 1009 and cysteine 1018
Cysteine 1505 and cysteine 1521
A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 299 and 312.

Details

Redox score ?
90
PDB code
5uk5
Structure name
complex of notch1(egf8-12) bound to jagged1(n-egf3)
Structure deposition date
2017-01-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
44
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q07008
Residue number A
299
Residue number B
312
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 299 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 312 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 266 and 281.

Details

Redox score ?
89
PDB code
5fma
Structure name
human notch 1, egf 4-7
Structure deposition date
2015-11-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
266
Residue number B
281
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 266 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 281 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 149 and 164.

Details

Redox score ?
89
PDB code
5fm9
Structure name
human notch 1, egf 4-7
Structure deposition date
2015-11-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
149
Residue number B
164
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 149 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 164 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 166 and 175.

Details

Redox score ?
89
PDB code
5fma
Structure name
human notch 1, egf 4-7
Structure deposition date
2015-11-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
166
Residue number B
175
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 166 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 175 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 227 and 243.

Details

Redox score ?
89
PDB code
5fma
Structure name
human notch 1, egf 4-7
Structure deposition date
2015-11-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
227
Residue number B
243
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 227 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 243 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 499 and 514.

Details

Redox score ?
89
PDB code
4cuf
Structure name
human notch1 egf domains 11-13 mutant t466s
Structure deposition date
2014-03-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
499
Residue number B
514
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 499 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 514 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 461 and 476.

Details

Redox score ?
88
PDB code
4d0e
Structure name
human notch1 egf domains 11-13 mutant glcnac-fucose disaccharide modified at t466
Structure deposition date
2014-04-25
Thiol separation (Å)
2
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
461
Residue number B
476
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 461 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 476 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 283 and 292.

Details

Redox score ?
88
PDB code
5fma
Structure name
human notch 1, egf 4-7
Structure deposition date
2015-11-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
45
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
283
Residue number B
292
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 283 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 292 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 1449 and 1472.

Details

Redox score ?
88
PDB code
7abv
Structure name
structure of the s1-cleaved mouse notch1 negative regulatory region (nrr)
Structure deposition date
2020-09-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q01705
Residue number A
1449
Residue number B
1472
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 1449 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1472 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 381 and 398.

Details

Redox score ?
88
PDB code
5uk5
Structure name
complex of notch1(egf8-12) bound to jagged1(n-egf3)
Structure deposition date
2017-01-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q07008
Residue number A
381
Residue number B
398
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 381 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 398 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 516 and 525.

Details

Redox score ?
88
PDB code
4cud
Structure name
human notch1 egf domains 11-13 mutant fucosylated at t466
Structure deposition date
2014-03-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
516
Residue number B
525
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 516 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 525 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 189 and 204.

Details

Redox score ?
88
PDB code
5fma
Structure name
human notch 1, egf 4-7
Structure deposition date
2015-11-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
189
Residue number B
204
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 189 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 204 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 245 and 254.

Details

Redox score ?
88
PDB code
5fma
Structure name
human notch 1, egf 4-7
Structure deposition date
2015-11-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
245
Residue number B
254
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 245 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 254 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 1454 and 1467 (1455 and 1468 respectively in this structure).

Details

Redox score ?
88
PDB code
3eto
Structure name
2 angstrom xray structure of the notch1 negative regulatory region (nrr)
Structure deposition date
2008-10-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
1454
Residue number B
1467
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 1454 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1467 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 206 and 215.

Details

Redox score ?
88
PDB code
5fma
Structure name
human notch 1, egf 4-7
Structure deposition date
2015-11-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
206
Residue number B
215
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 206 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 215 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 339 and 350.

Details

Redox score ?
88
PDB code
5uk5
Structure name
complex of notch1(egf8-12) bound to jagged1(n-egf3)
Structure deposition date
2017-01-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q07008
Residue number A
339
Residue number B
350
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 339 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 350 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 987 and 998 (969 and 980 respectively in this structure).

Details

Redox score ?
88
PDB code
5ky4
Structure name
mouse pofut1 in complex with mouse notch1 egf26 and gdp
Structure deposition date
2016-07-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q01705
Residue number A
987
Residue number B
998
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 987 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 998 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 478 and 487.

Details

Redox score ?
88
PDB code
4d0f
Structure name
human notch1 egf domains 11-13 mutant t466a
Structure deposition date
2014-04-25
Thiol separation (Å)
2
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
478
Residue number B
487
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 478 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 487 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 494 and 505.

Details

Redox score ?
88
PDB code
4d0f
Structure name
human notch1 egf domains 11-13 mutant t466a
Structure deposition date
2014-04-25
Thiol separation (Å)
2
Half-sphere exposure sum ?
48
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
494
Residue number B
505
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 494 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 505 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 416 and 429.

Details

Redox score ?
87
PDB code
4d0f
Structure name
human notch1 egf domains 11-13 mutant t466a
Structure deposition date
2014-04-25
Thiol separation (Å)
2
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
416
Residue number B
429
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 416 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 429 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 456 and 467.

Details

Redox score ?
87
PDB code
2vj3
Structure name
human notch-1 egfs 11-13
Structure deposition date
2007-12-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
49
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
456
Residue number B
467
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 456 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 467 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 423 and 438.

Details

Redox score ?
87
PDB code
4xlw
Structure name
complex of notch1 (egf11-13) bound to delta-like 4 (n-egf2)
Structure deposition date
2015-01-14
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q07008
Residue number A
423
Residue number B
438
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 423 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 438 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 182 and 195.

Details

Redox score ?
87
PDB code
5fma
Structure name
human notch 1, egf 4-7
Structure deposition date
2015-11-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
182
Residue number B
195
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 182 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 195 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 144 and 155.

Details

Redox score ?
87
PDB code
5fma
Structure name
human notch 1, egf 4-7
Structure deposition date
2015-11-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
144
Residue number B
155
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 144 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 155 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 306 and 321.

Details

Redox score ?
87
PDB code
5uk5
Structure name
complex of notch1(egf8-12) bound to jagged1(n-egf3)
Structure deposition date
2017-01-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q07008
Residue number A
306
Residue number B
321
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 306 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 321 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 344 and 359.

Details

Redox score ?
87
PDB code
5uk5
Structure name
complex of notch1(egf8-12) bound to jagged1(n-egf3)
Structure deposition date
2017-01-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q07008
Residue number A
344
Residue number B
359
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 344 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 359 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 440 and 449.

Details

Redox score ?
87
PDB code
5uk5
Structure name
complex of notch1(egf8-12) bound to jagged1(n-egf3)
Structure deposition date
2017-01-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q07008
Residue number A
440
Residue number B
449
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 440 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 449 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 222 and 233.

Details

Redox score ?
87
PDB code
5fma
Structure name
human notch 1, egf 4-7
Structure deposition date
2015-11-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
49
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
222
Residue number B
233
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 222 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 233 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 261 and 272.

Details

Redox score ?
87
PDB code
5fma
Structure name
human notch 1, egf 4-7
Structure deposition date
2015-11-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
47
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
261
Residue number B
272
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 261 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 272 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 400 and 409.

Details

Redox score ?
86
PDB code
5uk5
Structure name
complex of notch1(egf8-12) bound to jagged1(n-egf3)
Structure deposition date
2017-01-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q07008
Residue number A
400
Residue number B
409
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 400 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 409 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 361 and 370.

Details

Redox score ?
86
PDB code
5uk5
Structure name
complex of notch1(egf8-12) bound to jagged1(n-egf3)
Structure deposition date
2017-01-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q07008
Residue number A
361
Residue number B
370
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 361 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 370 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 1490 and 1514.

Details

Redox score ?
86
PDB code
7abv
Structure name
structure of the s1-cleaved mouse notch1 negative regulatory region (nrr)
Structure deposition date
2020-09-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q01705
Residue number A
1490
Residue number B
1514
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 1490 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1514 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 376 and 387.

Details

Redox score ?
85
PDB code
5uk5
Structure name
complex of notch1(egf8-12) bound to jagged1(n-egf3)
Structure deposition date
2017-01-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q07008
Residue number A
376
Residue number B
387
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 376 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 387 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 1192 and 476 (461 and 476 respectively in this structure).

Details

Redox score ?
85
PDB code
5ky9
Structure name
mouse pofut1 in complex with mouse notch1 egf12 mutant (d464g/a465g) and gdp
Structure deposition date
2016-07-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q01705
Residue number A
1192
Residue number B
476
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 1192 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 476 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 323 and 332.

Details

Redox score ?
84
PDB code
5uk5
Structure name
complex of notch1(egf8-12) bound to jagged1(n-egf3)
Structure deposition date
2017-01-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q07008
Residue number A
323
Residue number B
332
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 323 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 332 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 992 and 1007 (974 and 989 respectively in this structure).

Details

Redox score ?
84
PDB code
5ky4
Structure name
mouse pofut1 in complex with mouse notch1 egf26 and gdp
Structure deposition date
2016-07-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q01705
Residue number A
992
Residue number B
1007
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 992 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1007 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 1496 and 1509 (1497 and 1510 respectively in this structure).

Details

Redox score ?
84
PDB code
3eto
Structure name
2 angstrom xray structure of the notch1 negative regulatory region (nrr)
Structure deposition date
2008-10-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
P46531
Residue number A
1496
Residue number B
1509
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 1496 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1509 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 456 and 1198 (456 and 467 respectively in this structure).

Details

Redox score ?
84
PDB code
5ky9
Structure name
mouse pofut1 in complex with mouse notch1 egf12 mutant (d464g/a465g) and gdp
Structure deposition date
2016-07-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q01705
Residue number A
456
Residue number B
1198
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 456 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1198 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 1009 and 1018 (991 and 1000 respectively in this structure).

Details

Redox score ?
84
PDB code
5ky4
Structure name
mouse pofut1 in complex with mouse notch1 egf26 and gdp
Structure deposition date
2016-07-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q01705
Residue number A
1009
Residue number B
1018
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 1009 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1018 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 1 between cysteines 1505 and 1521.

Details

Redox score ?
84
PDB code
7abv
Structure name
structure of the s1-cleaved mouse notch1 negative regulatory region (nrr)
Structure deposition date
2020-09-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
48
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q01705
Residue number A
1505
Residue number B
1521
Peptide name
Neurogenic locus notch homolog protein 1

Ligandability

Cysteine 1505 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1521 of Neurogenic locus notch homolog protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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