a tool for identifying drug-targetable redox-active disulphides

B1 bradykinin receptor

Intramolecular

Cysteine 110 and cysteine 189

A redox-regulated disulphide may form within B1 bradykinin receptor between cysteines 110 and 189.

Details

Redox score ?

82

PDB code

Structure name

cryo-em structure of the type 1 bradykinin receptor in complex with the des-arg10-kallidin and an gq protein

Structure deposition date

2021-03-30

Thiol separation (Å)

2

Half-sphere exposure sum ?

81

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

110

Residue number B

189

Peptide name

B1 bradykinin receptor

Ligandability

Cysteine 110 of B1 bradykinin receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 189 of B1 bradykinin receptor

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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