Ras GTPase-activating-like protein IQGAP1

Intramolecular

A redox-regulated disulphide may form within Ras GTPase-activating-like protein IQGAP1 between cysteines 148 and 151. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

3i6x

Structure name

crystal structure of the calponin homology domain of iqgap1

Structure deposition date

2009-07-07

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

100

Peptide accession

P46940

Residue number A

148

Residue number B

151

Peptide name

Ras GTPase-activating-like protein IQGAP1

Ligandability

Cysteine 148 of Ras GTPase-activating-like protein IQGAP1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.