ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Eukaryotic translation initiation factor 1A, X-chromosomal

Intramolecular
Cysteine 51 and cysteine 59
A redox-regulated disulphide may form within Eukaryotic translation initiation factor 1A, X-chromosomal between cysteines 51 and 59. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
48
PDB code
4kzy
Structure name
rabbit 40s ribosomal subunit in complex with eif1 and eif1a
Structure deposition date
2013-05-30
Thiol separation (Å)
8
Half-sphere exposure sum ?
73
Minimum pKa ?
9
% buried
60
Peptide accession
P47813
Residue number A
51
Residue number B
59
Peptide name
Eukaryotic translation initiation factor 1A, X-chromosomal

Ligandability

Cysteine 51 of Eukaryotic translation initiation factor 1A, X-chromosomal

Cysteine 59 of Eukaryotic translation initiation factor 1A, X-chromosomal

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