P2Y purinoceptor 1
Intramolecular
Cysteine 42 and cysteine 296
Cysteine 1009 and cysteine 124
Cysteine 124 and cysteine 202
Cysteine 124 and cysteine 1042
Cysteine 1006 and cysteine 1009
4xnw A 42 A 296
A redox-regulated disulphide may form within P2Y purinoceptor 1 between cysteines 42 and 296.
Details
Redox score ?
89
PDB code
4xnw
Structure name
the human p2y1 receptor in complex with mrs2500
Structure deposition date
2015-01-16
Thiol separation (Å)
2
Half-sphere exposure sum ?
46
Minimum pKa ?
nan
% buried
nan
Peptide accession
P47900
Residue number A
42
Residue number B
296
Peptide name
P2Y purinoceptor 1
Ligandability
Cysteine 42 of P2Y purinoceptor 1
Cysteine 296 of P2Y purinoceptor 1
4xnw A 1009 A 1039
A redox-regulated disulphide may form within P2Y purinoceptor 1 between cysteines 1009 and 124 (1009 and 1039 respectively in this structure).
Details
Redox score ?
88
PDB code
4xnw
Structure name
the human p2y1 receptor in complex with mrs2500
Structure deposition date
2015-01-16
Thiol separation (Å)
3
Half-sphere exposure sum ?
47
Minimum pKa ?
6
% buried
3
Peptide accession
P47900
Residue number A
1009
Residue number B
124
Peptide name
P2Y purinoceptor 1
Ligandability
Cysteine 1009 of P2Y purinoceptor 1
Cysteine 124 of P2Y purinoceptor 1
Cysteine 1009 in protein A could not be asigned to a Uniprot residue.
4xnv A 124 A 202
A redox-regulated disulphide may form within P2Y purinoceptor 1 between cysteines 124 and 202.
Details
Redox score ?
82
PDB code
4xnv
Structure name
the human p2y1 receptor in complex with bptu
Structure deposition date
2015-01-16
Thiol separation (Å)
2
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P47900
Residue number A
124
Residue number B
202
Peptide name
P2Y purinoceptor 1
Ligandability
Cysteine 124 of P2Y purinoceptor 1
Cysteine 202 of P2Y purinoceptor 1
4xnw A 1039 A 1042
A redox-regulated disulphide may form within P2Y purinoceptor 1 between cysteines 124 and 1042 (1039 and 1042 respectively in this structure).
Details
Redox score ?
nan
PDB code
4xnw
Structure name
the human p2y1 receptor in complex with mrs2500
Structure deposition date
2015-01-16
Thiol separation (Å)
4
Half-sphere exposure sum ?
44
Minimum pKa ?
6
% buried
3
Peptide accession
P47900
Residue number A
124
Residue number B
1042
Peptide name
P2Y purinoceptor 1
Ligandability
Cysteine 124 of P2Y purinoceptor 1
Cysteine 1042 of P2Y purinoceptor 1
Cysteine 1042 in protein B could not be asigned to a Uniprot residue.
4xnw A 1006 A 1009
A redox-regulated disulphide may form within P2Y purinoceptor 1 between cysteines 1006 and 1009.
Details
Redox score ?
nan
PDB code
4xnw
Structure name
the human p2y1 receptor in complex with mrs2500
Structure deposition date
2015-01-16
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
8
% buried
0
Peptide accession
P47900
Residue number A
1006
Residue number B
1009
Peptide name
P2Y purinoceptor 1
Ligandability
Cysteine 1006 of P2Y purinoceptor 1
Cysteine 1009 of P2Y purinoceptor 1
Cysteine 1006 in protein A could not be asigned to a Uniprot residue.
Cysteine 1009 in protein B could not be asigned to a Uniprot residue.
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